Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (PGT122) (CAT#: PFBZ-161)

Recombinant Human Antibody (PGT122) Fab Fragment is specific to HIV-1 gp120, expressed in Chinese Hamster Ovary cells (CHO). PGT121 family, which was previously shown to neutralize approximately 70% of circulating HIV-1 isolates and recognizes an N332-dependent epitope on the gp120 outer domain. PGT121 antibodies inhibit CD4 binding to gp120 despite the epitope being distal from the CD4 binding site.

Specific Inquiry
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  • Datasheet
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Specifications

  • Immunogen
  • HIV-1 gp160; envelope glycoprotein
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Fab
  • Specificity
  • Tested positive against native HIV-1 gp120
  • Species Reactivity
  • HIV-1
  • Clone
  • PGT122
  • Applications
  • Can be useful in applications such as: Flow Cytometry, Neutralization

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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AGTO-L012R anti-env immunotoxin 907 (IgG)-RTA Cytotoxicity assay, Functional assay

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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