PE-H-2Dd/HIV Env (IPGRAFYA) MHC Tetramer
CAT#: MHC-CN0617
Specifications
- Allele
- H-2Dd
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Env
- Antigen Species
- HIV
- Peptide
- IPGRAFYA
- Conjugate
- PE
- Application
- FCM, IHC
Target
- Antigen Introduction
- The env gene codes for the gp160 protein which forms a homotrimer, and is cleaved into gp120 and gp41 by the host cell protease, Furin. To form an active fusion protein, gp120 and gp41 polypeptides remain non-covalently bound together, but this interaction is often not stable, leading to shed, soluble gp120 and membrane-bound, gp41 'stumps'. Separately, cleavage by furin is inefficient, and virions often are released with inactive, uncleaved gp160. Because of the high prevalence of these inactive forms, the immune system often produces antibodies which target inactive Env, rather than active forms of the envelope protein.
- Alternative Names
- ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160; precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain
- Gene ID
- 155971
- UniProt ID
- P04578
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Datasheet
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L012R | anti-env immunotoxin 907 (IgG)-RTA | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-193 | Recombinant Human Anti-HIV-1 gp41-M-MAT Antibody Fab Fragment | Neut, FuncS | Fab |
| PSBZ-141 | Human Anti-ENV Recombinant Antibody (clone 2F5); scFv Fragment | Neut | Human scFv |
| PSBZ-168 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (PGT 135) | ELISA, Neut | scFv |
| PSBZ-169 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (45-46M2) | ELISA, Neut | scFv |
| PSBZ-205 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (PGT121) | Neut, ELISA | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-020 | Recombinant Anti-HIV ENV VHH Single Domain Antibody (PNBL-020) | ELISA, SPR, Neut, FuncS | Llama VHH |
| PNBL-021 | Recombinant Anti-HIV-1 ENV VHH Single Domain Antibody (PNBL-021) | Neut, WB, ELISA, FuncS | Llama VHH |
| PNBL-059 | Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody (PNBL-059) | ELISA, Inhib | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-438 | Recombinant Human Anti-DENV Env Antibody (PABL-438) | Neut | IgG |
| PABL-439 | Human Anti-Env Recombinant Antibody (PABL-439) | Neut | Human IgG |
| PABL-440 | Human Anti-Env Recombinant Antibody (PABL-440) | ELISA | Human IgG |
| PABL-441 | Human Anti-Env Recombinant Antibody (PABL-441) | Neut | Human IgG |
| PABL-442 | Recombinant Mouse Anti-DENV type 4 envelope protein domain III Antibody (Mab513) | WB, IHC, IF, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-141 | Human Anti-ENV Recombinant Antibody (clone 2F5); Fab Fragment | Neut | Human Fab |
| PFBZ-160 | Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (PGT123) | FACS, Neut | Fab |
| PFBZ-161 | Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (PGT122) | FACS, Neut | Fab |
| PFBZ-168 | Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (PGT 135) | ELISA, Neut | Fab |
| PFBZ-169 | Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (45-46M2) | ELISA, Neut | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF410 | A*02:01/HIV Env (SLLNATAIAV) MHC Pentamer | FCM | |
| MHC-YF411 | A*29:02/HIV Env (SFDPIPIHY) MHC Pentamer | FCM | |
| MHC-YF412 | A*29:02/HIV Env (SFNCRGEFFY) MHC Pentamer | FCM | |
| MHC-YF413 | B*08:01/HIV Env (YLKDQQLL) MHC Pentamer | FCM | |
| MHC-YF497 | H-2Dd/HIV IIIB gp120 (RGPGRAFVTI) MHC Pentamer | FCM |
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