This immunotoxin was achieved by conjugating/fusing the Anti-env monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to cells infected with HIV. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of AIDS.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-193 | Recombinant Human Anti-HIV-1 gp41-M-MAT Antibody scFv Fragment | Neut, FuncS | scFv |
PFBZ-169 | Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (45-46M2) | ELISA, Neut | Fab |
PFBZ-205 | Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (PGT121) | Neut, ELISA | Fab |
PFBW-167 | Recombinant Human Anti-HIV-1 gp120 Antibody Fab Fragment (537-10D) | ELISA, Neut | Fab |
PSBL-572 | Recombinant Human Anti-HPV Env Antibody scFv Fragment (mAb-94) | WB, IF, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PNBL-020 | Recombinant Anti-HIV ENV VHH Single Domain Antibody (JM4) | ELISA, SPR, Neut, FuncS | Llama VHH |
PNBL-021 | Recombinant Anti-HIV-1 ENV VHH Single Domain Antibody (2H10) | Neut, WB, ELISA, FuncS | Llama VHH |
PNBL-059 | Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody (D7) | ELISA, Inhib | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
PABZ-141 | Human Anti-ENV Recombinant Antibody (clone 2F5) | Neut | Human IgG |
PABZ-160 | Recombinant Human Anti-HIV-1 gp120 Antibody (PGT123) | FACS, Neut | IgG |
PABZ-161 | Recombinant Human Anti-HIV-1 gp120 Antibody (PGT122) | FACS, Neut | IgG |
PABZ-168 | Recombinant Human Anti-HIV-1 gp120 Antibody (PGT 135) | ELISA, Neut | IgG |
PABZ-169 | Recombinant Human Anti-HIV-1 gp120 Antibody (45-46M2) | ELISA, Neut | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-435 | Recombinant Human Anti-DENV Env Antibody Fab Fragment (EDE1 A11) | Neut | Fab |
PFBL-436 | Human Anti-Env Recombinant Antibody; Fab Fragment (PFBL-436) | Neut | Human Fab |
PSBZ-168 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (PGT 135) | ELISA, Neut | scFv |
PSBZ-169 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (45-46M2) | ELISA, Neut | scFv |
PSBZ-205 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (PGT121) | Neut, ELISA | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-YF410 | A*02:01/HIV Env (SLLNATAIAV) MHC Pentamer | FCM | |
MHC-YF411 | A*29:02/HIV Env (SFDPIPIHY) MHC Pentamer | FCM | |
MHC-YF412 | A*29:02/HIV Env (SFNCRGEFFY) MHC Pentamer | FCM | |
MHC-YF413 | B*08:01/HIV Env (YLKDQQLL) MHC Pentamer | FCM | |
MHC-YF497 | H-2Dd/HIV IIIB gp120 (RGPGRAFVTI) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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