Recombinant Mouse anti-Human HDAC6 Monoclonal antibody (EML1253)
CAT#: MOB-0143CT
Recombinant Mouse monoclonal antibody to Human HDAC6, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26321/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4236/12458_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4236/12458_A_7_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4236/12458_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4236/12458_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000094631-HDAC6
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Specifications
- Immunogen
- Recombinant fragment: DVTQPCGDCG TIQENWVCLS CYQVYCGRYI NGHMLQHHGN SGHPLVLSYI DLSAWCYYCQ AYVHHQALLD VKNIAHQNKF GEDMPHPH, corresponding to amino acids 1128-1216 of Human HDAC6
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- EML1253
- Applications
- Used for immunoassay techniques such as: Immunocytochemistry/Immunofluorescence; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 0.5 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- HDAC6; histone deacetylase 6; HD6; JM21; CPBHM; PPP1R90; protein phosphatase 1, regulatory subunit 90;
- Gene ID
- 10013
- UniProt ID
- Q9UBN7
- Protein Refseq
- NP_006035
- Function
- Hsp90 protein binding; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); actin binding; alpha-tubulin binding; beta-cate
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Related Diseases
Alcoholism
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "HDAC6"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1577 | Rabbit Anti-HDAC6 Recombinant Antibody (clone DS1577AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0722-CN | Rabbit Anti-HDAC6 Recombinant Antibody (clone CBACN-261) | WB, IF, IHC, IP | Rabbit IgG |
| ZG-0097C | Mouse Anti-HDAC6 Recombinant Antibody (clone ABT-HDAC6) | IHC-P, IF | Mouse IgG |
| VS3-QX508 | Mouse Anti-HDAC6 Recombinant Antibody (clone 3B2-F5-G6) | WB | Mouse IgG2a |
| VS3-FY663 | Recombinant Mouse Anti-HDAC6 Antibody (clone 10G7-4D10-6A7) | IHC-P | Mouse IgG1 |
| VS3-XY3377 | Rabbit Anti-HDAC6 Recombinant Antibody (clone R07-2H6) | WB, IHC-P, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY241 | Mouse Anti-NHP HDAC6 Recombinant Antibody (clone OTI4C5) | WB, IHC, IF, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1004 | Anti-HDAC6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3101 | Anti-Human HDAC6 Immunohistochemistry Kit | IHC |
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