Recombinant Mouse anti-Human PDE1B Monoclonal antibody (EML606) (CAT#: MOB-1325CT)
Recombinant Mouse monoclonal antibody to Human PDE1B, expressed in Chinese Hamster Ovary cells(CHO).
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in caudate nucleus
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_7_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_7_selected.jpg
Figure 2 Low expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_3_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_3_3_val_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_5.jpg
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_5.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_9_5.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_6_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123360-PDE1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123360-PDE1B
Specifications
- Immunogen
- Recombinant fragment: TDVAEKSVQP LADEDSKSKN QPSFQWRQPS LDVEVGDPNP DVVSFRSTWV KRIQENKQKW KERAASGITN QMSIDELSPC EEEAPPSPAE DEHNQNGNLD , corresponding to amino acids 437-536 of Human PDE1B
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- EML606
- Applications
- Used for immunoassay techniques such as: Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- PDE1B; phosphodiesterase 1B, calmodulin-dependent; PDE1B1; PDES1B; calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1B; cam-PDE 1B; 63 kDa Cam-PDE; calmodulin-stimulated phosphodiesterase PDE1B1; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B;
- Gene ID
- 5153
- UniProt ID
- Q01064
- Protein Refseq
- NP_000915
- Function
- 3,5-cyclic-AMP phosphodiesterase activity; calcium- and calmodulin-regulated 3,5-cyclic-GMP phosphodiesterase activity; calmodulin binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; hydrolase activity; metal ion binding;
Related Resources
cAMP Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PDE1B"
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2628 | Hi-Affi™ Recombinant Rabbit Anti-PDE1B Monoclonal Antibody (DS2628AB) | WB, IHC-P | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1224 | Mouse Anti-PDE1B Recombinant Antibody (clone 5C4A3) | IHC, FC | Mouse IgG1 |
| VS3-XY1226 | Mouse Anti-PDE1B Recombinant Antibody (clone 5A11) | ELISA, WB, FC | Mouse IgG1 |
| VS3-XY1227 | Mouse Anti-PDE1B Recombinant Antibody (clone 5G9) | ELISA, WB, FC, IHC | Mouse IgG1 |
| VS3-XY1228 | Mouse Anti-PDE1B Recombinant Antibody (clone 5H6D4) | ELISA, WB, FC | Mouse IgG1 |
| VS3-XY1229 | Mouse Anti-PDE1B Recombinant Antibody (clone 8F11) | ELISA, WB, FC, IHC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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