Recombinant Mouse anti-Human PDE1B Monoclonal antibody (EML606) (CAT#: MOB-1325CT)
Recombinant Mouse monoclonal antibody to Human PDE1B, expressed in Chinese Hamster Ovary cells(CHO).
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Normal Tissue
RNA Expression
Figure 1 High expression in caudate nucleus
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_7_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_7_selected.jpg
Figure 2 Low expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_3_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_3_3_val_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_5.jpg
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_5.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_9_5.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_6_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123360-PDE1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123360-PDE1B
Specifications
- Immunogen
- Recombinant fragment: TDVAEKSVQP LADEDSKSKN QPSFQWRQPS LDVEVGDPNP DVVSFRSTWV KRIQENKQKW KERAASGITN QMSIDELSPC EEEAPPSPAE DEHNQNGNLD , corresponding to amino acids 437-536 of Human PDE1B
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- EML606
- Applications
- Used for immunoassay techniques such as: Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- PDE1B; phosphodiesterase 1B, calmodulin-dependent; PDE1B1; PDES1B; calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1B; cam-PDE 1B; 63 kDa Cam-PDE; calmodulin-stimulated phosphodiesterase PDE1B1; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B;
- Gene ID
- 5153
- UniProt ID
- Q01064
- Protein Refseq
- NP_000915
- Function
- 3,5-cyclic-AMP phosphodiesterase activity; calcium- and calmodulin-regulated 3,5-cyclic-GMP phosphodiesterase activity; calmodulin binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; hydrolase activity; metal ion binding;
Related Resources
cAMP Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2628 | Hi-Affi™ Recombinant Rabbit Anti-PDE1B Monoclonal Antibody (DS2628AB) | WB, IHC-P | IgG |
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