Mouse Anti-NHP PDE1B Recombinant Antibody (clone OTI6B9) (CAT#: VS-1024-XY371)
Designed for the specific detection of PDE1B, this mouse monoclonal antibody showcases reactivity with dog, human, non-human primate, and rat tissues. The immunogen is a full-length recombinant human PDE1B protein, ensuring optimal specificity. Versatile in its applications, this antibody is suitable for Western blot (WB), immunocytochemistry (ICC), and flow cytometry (FC), making it an essential tool for exploring PDE1B expression and functionality in various biological research contexts.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in caudate nucleus
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_7_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_7_selected.jpg
Figure 2 Low expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_3_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_3_3_val_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_5.jpg
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_B_9_5.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_9_5.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_6_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18492/167689_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123360-PDE1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123360-PDE1B
Specifications
- Immunogen
- Full length human recombinant protein of PDE1B
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- PDE1B
- Species Reactivity
- Dog, Human, Non-human primate, Rat
- Clone
- OTI6B9
- Applications
- WB, ICC, FC
Product Property
- Purification
- Protein A purified
- Purity
- >95%, determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS, pH 7.4, with 1% BSA, 50% glycerol
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- WB: 1:500-1:20, ICC: 1:100, FC: 1:100
Target
- Alternative Names
- Phosphodiesterase 1B; Phosphodiesterase 1B; Calmodulin-Dependent; 3 KDa Cam-PDE; EC 3.1.4.17; Cam-PDE 1B; PDES1B; PDE1B1; Presumed 63kDa Form Of The Type 1 Cyclic Nucleotide Phosphodiesterase Family Known As PDE1B;
- Gene ID
- 5153
- UniProt ID
- Q01064
Recommended Products
Recommended Dilution Buffer
Isotype Control
Secondary Antibody
Related Resources
cAMP Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2628 | Hi-Affi™ Recombinant Rabbit Anti-PDE1B Monoclonal Antibody (DS2628AB) | WB, IHC-P | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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