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PDE1B
Loading...Anti-PDE1B Products
- Mouse Anti-PDE1B Recombinant Antibody (clone 8F11) (VS3-XY1229)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC, IHC
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- Mouse Anti-PDE1B Recombinant Antibody (clone 5H6D4) (VS3-XY1228)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
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- Mouse Anti-PDE1B Recombinant Antibody (clone 5G9) (VS3-XY1227)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC, IHC
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- Mouse Anti-PDE1B Recombinant Antibody (clone 5A11) (VS3-XY1226)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
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- Mouse Anti-PDE1B Recombinant Antibody (clone 5C4A3) (VS3-XY1224)
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- Type: Mouse IgG1
- Application: IHC, FC
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- Mouse Anti-NHP PDE1B Recombinant Antibody (clone OTI6B9) (VS-1024-XY371)
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- Species Reactivity: Dog, Human, Non-human primate, Rat
- Type: Mouse IgG2b
- Application: WB, ICC, FC
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- Anti-PDE1B Immunohistochemistry Kit (VS-0525-XY5265)
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- Species Reactivity: Human
- Target: PDE1B
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Protein class
Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Excitatory neurons, Smooth muscle cells, Sertoli cells, Kupffer cells, Inhibitory neurons, Macrophages)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HDLM-2, HMC-1, NB-4, THP-1, U-937)
Interaction
Homodimer.
Molecular function
Calmodulin-binding, Hydrolase
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway