Anti-Human IL-1α (Interleukin 1 alpha) Recombinant Antibody Fab Fragment (TAB-227CT-F(E))

CAT#: TAB-227CT-F(E)

Recombinant monoclonal antibody to interleukin 1 alpha. This antibody intended for the prophylaxis and treatment of Crohn's disease.

Gene Expression
Figure 1 RNA cell line category: Group enriched (HBEC3-KT, hTCEpi, hTERT-HME1)

Specifications

  • Immunogen
  • Recombinant purified human IL-1α
  • Host Species
  • Mouse
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Applications
  • Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Neutralization
  • Related Disease
  • Crohn's disease

Target

  • Alternative Names
  • The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimers disease.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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