Human Anti-IL23R Recombinant Antibody; Fab Fragment (TAB-624LC-F(E)) (CAT#: TAB-624LC-F(E))
This is a recombinant antibody Fab fragment specific for IL-23R (Interleukin 23 receptor), derived from human. The antibody was purified by affinity chromatography. It recognizes IL-23R and has species cross-reactivity against human or monkey IL23R. It has been detected by Enzyme-linked immunosorbent assay and Flow cytometry.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human bronchus
(Immunohistochemical staining of human bronchus shows distinct positivity in a subset of leukocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/ihc_selected.jpg
(Immunohistochemical staining of human bronchus shows distinct positivity in a subset of leukocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_B_7_5.jpg
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_B_7_5.jpg
Figure 3 Colon
(Endothelial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_9_3.jpg
(Endothelial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_9_3.jpg
Figure 4 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_8_5.jpg
Figure 5 Testis
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_6_6.jpg
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HL-60, HMC-1, K-562, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000162594-IL23R
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000162594-IL23R
Specifications
- Immunogen
- Human IL-23R-Fc fusion protein
- Host Species
- Human
- Type
- Chimeric (mouse/human) Fab
- Specificity
- Human
- Species Reactivity
- Human
- Applications
- ELISA, FC
- Related Disease
- Ophthalmic disease, inflammatory bowel disease and psoriasis
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL23R; interleukin 23 receptor; interleukin-23 receptor; IL-23 receptor
- Gene ID
- 149233
- UniProt ID
- Q5VWK5
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3520z | Mouse Anti-IL23R Recombinant Antibody (clone 20H11) | WB, IP, ELISA | Mouse IgG2a, κ |
| HPAB-0330-CN | Mouse Anti-IL23R Recombinant Antibody (clone TC48-8B10.D5) | ELISA, FC, IP, Agonist | Mouse IgG |
| HPAB-0031-WJ | Mouse Anti-IL23R Recombinant Antibody (clone 9H3) | ELISA, WB | Mouse IgG1, κ |
| PABS-0009 | Camelid Anti-IL23R Recombinant Single Domain Antibody (Clone 22E11) | ELISA, FuncS | Camelid VHH |
| MOB-348YC | Mouse Anti-IL23R Recombinant Antibody (MOB-348YC) | WB, IHC-P | Mouse IgG1 kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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