What diseases is the target of this antibody associated with?

The target, IL23R, is associated with ophthalmic disease, inflammatory bowel disease, and psoriasis. It is a receptor for the cytokine IL23 and pairs with IL12RB1.

How is this antibody purified and what are its applications?

This recombinant human antibody is purified using affinity chromatography, which ensures a high degree of purity and specificity for your experiments. It has been experimentally determined and validated for use in key research applications, specifically Enzyme-linked Immunosorbent Assay (ELISA) and Flow Cytometry (FC), to facilitate your studies on the IL23R protein.

Human Anti-IL23R Recombinant Antibody (TAB-627LC)

CAT#: TAB-627LC

This product is a recombinant human antibody that recognizes IL-23R (Interleukin 23 receptor), which is the receptor of cytokine IL23. The antibody was purified by affinity chromatography. It is capable of studying various diseases such as ophthalmic disease, inflammatory bowel disease. It has been determined using Enzyme-linked immunosorbent assay and Flow cytometry.

Gene Expression

Normal Tissue Figure 1 IHC staining of human bronchus

Immunohistochemical staining of human bronchus shows distinct positivity in a subset of leukocytes.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/ihc_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_B_7_5.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_9_3.jpg

Normal Tissue Figure 4 Kidney

Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_8_5.jpg

Normal Tissue Figure 5 Testis

Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_6_6.jpg

RNA Expression Figure 6 RNA cell line category: Cell line enhanced (HL-60, HMC-1, K-562, U-2197)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000162594-IL23R

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Specifications

Host Species
Human

Type
Human IgG

Specificity
Human

Species Reactivity
Human

Applications
ELISA, FC

Related Disease
Ophthalmic disease, inflammatory bowel disease and psoriasis

Product Property

Purity
>95% as determined by SDS-PAGE

Buffer
PBS

Preservative
No preservatives

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
IL23R; interleukin 23 receptor; interleukin-23 receptor; IL-23 receptor

Gene ID
149233

UniProt ID
Q5VWK5

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Breast cancer biomarkers at key points during disease progression

Effective Flow Cytometry Reagent

We used this recombinant human antibody to detect IL23R on cell surfaces using Flow Cytometry. It recognized the receptor specifically, helping us study the IL23 signaling pathway. The affinity purified antibody gave clean results, which is essential for our research on inflammatory bowel disease models.

Q&As

What diseases is the target of this antibody associated with?

A: The target, IL23R, is associated with ophthalmic disease, inflammatory bowel disease, and psoriasis. It is a receptor for the cytokine IL23 and pairs with IL12RB1.
How is this antibody purified and what are its applications?

A: This recombinant human antibody is purified using affinity chromatography, which ensures a high degree of purity and specificity for your experiments. It has been experimentally determined and validated for use in key research applications, specifically Enzyme-linked Immunosorbent Assay (ELISA) and Flow Cytometry (FC), to facilitate your studies on the IL23R protein.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-627LC.pdf

MSDS

MSDS - TAB-627LC.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

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TAB-626LC	Human Anti-IL23R Recombinant Antibody (TAB-626LC)	ELISA, FC	Human IgG

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TAB-626LC-S(P)	Human Anti-IL23R Recombinant Antibody; scFv Fragment (TAB-626LC-S(P))	ELISA, FC	Human scFv

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TAB-629LC-S(P)	Anti-human IL23R scFv Fragment (TAB-629LC-S(P))	ELISA	Humanized antibody

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TAB-630LC-S(P)	Anti-human IL23R scFv Fragment (TAB-630LC-S(P))	ELISA	Humanized antibody

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HPAB-0031-WJ-S(P)	Mouse Anti-IL23R Recombinant Antibody (clone 9H3); scFv Fragment	ELISA, WB	Mouse scFv

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HPAB-1239-FY-F(E)	Human Anti-IL23R Recombinant Antibody Fab Fragment (HPAB-1239-FY-F(E))	Block	Humanized Fab

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HPAB-1240-FY-F(E)	Rat Anti-IL23R Recombinant Antibody Fab Fragment (HPAB-1240-FY-F(E))	Block	Rat Fab

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HPAB-1238-FY-S(P)	Rat Anti-IL23R Recombinant Antibody scFv Fragment (HPAB-1238-FY-S(P))	Block	Rat scFv

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HPAB-1239-FY-S(P)	Human Anti-IL23R Recombinant Antibody scFv Fragment (HPAB-1239-FY-S(P))	Block	Humanized scFv

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HPAB-1240-FY-S(P)	Rat Anti-IL23R Recombinant Antibody scFv Fragment (HPAB-1240-FY-S(P))	Block	Rat scFv

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VS-0424-XY149	AbPlus™ Anti-IL23R Magnetic Beads (TC48-8B10.D5)	IP, Protein Purification

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