What is the specificity and host of this antibody?

This is a recombinant antibody specific for Human IL-23R (Interleukin 23 receptor). It is derived from human and is an IgG isotype.

What are the applications for this IL23R antibody?

It can be used for Enzyme-linked immunosorbent assay (ELISA) and Flow cytometry (FC). It has excellent activity against IL23R.

Human Anti-IL23R Recombinant Antibody (TAB-625LC)

CAT#: TAB-625LC

This is a recombinant antibody specific for IL-23R (Interleukin 23 receptor), derived from human. The antibody was purified by affinity chromatography. It specifically recognizes IL-23R. It has excellent activity agaisnt IL23R. It can be used for Enzyme-linked immunosorbent assay, Flow cytometry and other applications.

Gene Expression

Normal Tissue Figure 1 IHC staining of human bronchus

Immunohistochemical staining of human bronchus shows distinct positivity in a subset of leukocytes.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/ihc_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_B_7_5.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_9_3.jpg

Normal Tissue Figure 4 Kidney

Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_8_5.jpg

Normal Tissue Figure 5 Testis

Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_6_6.jpg

RNA Expression Figure 6 RNA cell line category: Cell line enhanced (HL-60, HMC-1, K-562, U-2197)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000162594-IL23R

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Specifications

Host Species
Human

Type
Human IgG

Antibody Isotype
IgG

Specificity
Human

Species Reactivity
Human

Applications
ELISA, FC

Related Disease
Ophthalmic disease, inflammatory bowel disease and psoriasis

Product Property

Purity
>95% as determined by SDS-PAGE

Buffer
PBS

Preservative
No preservatives

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
IL23R; interleukin 23 receptor; interleukin-23 receptor; IL-23 receptor

Gene ID
149233

UniProt ID
Q5VWK5

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Breast cancer biomarkers at key points during disease progression

High Activity Against IL23R

This human recombinant antibody showed excellent activity against the IL-23 receptor in our assays. We used it for Flow Cytometry and saw a distinct shift in positive populations. It is a robust reagent for studying inflammatory pathways.

Sensitive ELISA Detection

We validated this antibody in an ELISA setup for IL23R. It bound specifically and allowed for sensitive detection. The affinity purification seems to have resulted in a very high-quality product that meets our research standards.

Q&As

What is the specificity and host of this antibody?

A: This is a recombinant antibody specific for Human IL-23R (Interleukin 23 receptor). It is derived from human and is an IgG isotype.
What are the applications for this IL23R antibody?

A: It can be used for Enzyme-linked immunosorbent assay (ELISA) and Flow cytometry (FC). It has excellent activity against IL23R.

View the frequently asked questions answered by Creative Biolabs Support.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-625LC, RRID: AB_3714470)

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-625LC.pdf

MSDS

MSDS - TAB-625LC.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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TAB-625LC-S(P)	Human Anti-IL23R Recombinant Antibody; scFv Fragment (TAB-625LC-S(P))	ELISA, FC	Human scFv

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TAB-626LC-S(P)	Human Anti-IL23R Recombinant Antibody; scFv Fragment (TAB-626LC-S(P))	ELISA, FC	Human scFv

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TAB-629LC-S(P)	Anti-human IL23R scFv Fragment (TAB-629LC-S(P))	ELISA	Humanized antibody

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