Human Anti-ITGA2B Recombinant Antibody (clone RUC-2); Fab Fragment (CAT#: PFBL-740)

Recombinant Human Antibody (RUC-2) is capable of binding to ITGA2B, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ITGA2B fab and CH1-3 region of human fab and a light chain (LC) encoding VL from anti-ITGA2B proteins fab and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody inhibits ligand binding by a mechanism different from that of all other α(IIb)β(3) antagonists and may offer advantages as a therapeutic agent.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • Human integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Human Fab
  • Specificity
  • Human ITGA2B
  • Species Reactivity
  • Human
  • Clone
  • RUC-2
  • Applications
  • Block

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • ITGA2B; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93; integrin alpha-IIb; GPalpha IIb; platelet-specific antigen BAK; platelet membrane glycoprotein IIb; platelet fibrinogen receptor, alpha subunit; protein phosphatase 1, regulatory subunit 93

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone RUC-2"

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Chimeric Antibody

CAT Product Name Application Type
TAB-015-F(E) Anti-Human CD41 Recombinant Antibody Fab Fragment (Abciximab) IP, IF, FuncS, FC, Neut, ELISA, ICC Fab - G1 - kappa

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1546CQ Recombinant Mouse Anti-ITGA2B Antibody (HIP8) CyTOF, FuncS, FC, IFC, IHC, Neut IgG1, κ

Blocking Antibody

CAT Product Name Application Type
NEUT-1547CQ Recombinant Mouse Anti-ITGA2B Antibody (PAC1) FC, IP, WB, BL IgM, κ
NEUT-1548CQ Recombinant Mouse Anti-ITGA2B Antibody (A2A9/6) FC, BL, IP IgG2a, κ

Rabbit Monoclonal Antibody

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0578CQ Recombinant Mouse Anti-Human ITGA2B Antibody (1E6) ELISA IgG2a

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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