Anti-Human CD41 Recombinant Antibody Fab Fragment (Abciximab) (CAT#: TAB-015-F(E))

Recombinant monoclonal antibody Fragment Fab to Human CD41. Abciximab (previously known as c7E3 Fab), a glycoprotein IIb/IIIa receptor antagonist, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery. It is a glycoprotein IIb/IIIa inhibitor.
While abciximab has a short plasma half-life, due to its strong affinity for its receptor on the platelets, it may occupy some receptors for weeks. In practice, platelet aggregation gradually returns to normal about 96 to 120 hours after discontinuation of the drug. E27-E35 Abciximab is made from the Fab Fragment of an immunoglobulin that targets the glycoprotein IIb/IIIa receptor on the platelet membrane.

Host: Mouse

Isotype: Fab - G1 - kappa

Applications: Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, WB and most other immunological methods.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Subcellular Location and Protein Expression

Normal Tissue

RNA Expression


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Fab - G1 - kappa
  • Specificity
  • Tested positive against native human antigen
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, WB and most other immunological methods.
  • Trade name
  • reopro
  • CAS
  • 143653-53-6
  • Generic Name
  • Abciximab
  • Biological Half-Life
  • <10 min–30 min
  • ATC Code
  • B01AC13
  • DrugBank
  • DB00054
  • UNII
  • X85G7936GV
  • ChEMBL
  • CHEMBL1201584
  • MW
  • 47455.4 g/mol
  • Related Disease
  • Refractory unstable angina when percutaneous coronary intervention is planned

Product Property

  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • Abciximab;reopro;143653-53-6;c7E3 Fab;c7E3 Fab;glycoprotein IIb/IIIa inhibitor;DB00054ITGA2B;integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41);GP2B, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen

Related Resources

  • Biosimilar Overview
Please refer to Abciximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Abciximab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "ITGA2B"

Fab Fragment Antibody

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PFBL-740 Human Anti-ITGA2B Recombinant Antibody (clone RUC-2); Fab Fragment Block Human Fab
HPAB-0275-YC-F(E) Mouse Anti-ITGA2B Recombinant Antibody; Fab Fragment (HPAB-0275-YC-F(E)) ELISA, FuncS Mouse Fab
HPAB-0276-YC-F(E) Mouse Anti-ITGA2B Recombinant Antibody; Fab Fragment (HPAB-0276-YC-F(E)) FuncS Mouse Fab
HPAB-0277-YC-F(E) Human Anti-ITGA2B Recombinant Antibody; Fab Fragment (HPAB-0277-YC-F(E)) FuncS Humanized Fab

scFv Fragment Antibody

CAT Product Name Application Type
PSBL-740 Human Anti-ITGA2B Recombinant Antibody (clone RUC-2); scFv Fragment Block Human scFv
HPAB-0275-YC-S(P) Mouse Anti-ITGA2B Recombinant Antibody; scFv Fragment (HPAB-0275-YC-S(P)) ELISA, FuncS Mouse scFv
HPAB-0276-YC-S(P) Mouse Anti-ITGA2B Recombinant Antibody; scFv Fragment (HPAB-0276-YC-S(P)) FuncS Mouse scFv
HPAB-0277-YC-S(P) Human Anti-ITGA2B Recombinant Antibody; scFv Fragment (HPAB-0277-YC-S(P)) FuncS Humanized scFv

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1546CQ Recombinant Mouse Anti-ITGA2B Antibody (HIP8) CyTOF, FuncS, FC, IFC, IHC, Neut IgG1, κ

Blocking Antibody

CAT Product Name Application Type
NEUT-1547CQ Recombinant Mouse Anti-ITGA2B Antibody (PAC1) FC, IP, WB, BL IgM, κ
NEUT-1548CQ Recombinant Mouse Anti-ITGA2B Antibody (A2A9/6) FC, BL, IP IgG2a, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1872 Hi-Affi™ Recombinant Rabbit Anti-ITGA2B Monoclonal Antibody (DS1872AB) WB, IHC IgG

Model Organism Antibody

CAT Product Name Application Type
MD-ZBF-YC012 Recombinant Mouse Anti-Zebrafish Itga2b Antibody FC Mouse antibody

Recombinant Antibody

CAT Product Name Application Type
HPAB-0275-YC Mouse Anti-ITGA2B Recombinant Antibody (HPAB-0275-YC) ELISA, FuncS Mouse IgG
HPAB-0276-YC Mouse Anti-ITGA2B Recombinant Antibody (HPAB-0276-YC) FuncS Mouse IgG1, κ
HPAB-0277-YC Human Anti-ITGA2B Recombinant Antibody (HPAB-0277-YC) FuncS Humanized IgG
MRO-0305-CN Recombinant Rabbit Anti-ITGA2B Monoclonal Antibody (JM11-19) WB, IHC Rabbit IgG
ZG-504C Mouse Anti-ITGA2B Recombinant Antibody (clone 2.41) ELISA Mouse IgG1, κ

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0578CQ Recombinant Mouse Anti-Human ITGA2B Antibody (1E6) ELISA IgG2a

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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