Human Anti-ITGAL Recombinant Antibody (clone AL-57); scFv Fragment
CAT#: PSBW-159
Recombinant Human Antibody (AL-57) is capable of binding to ITGAL, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ITGAL scFv and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-ITGAL proteins scFv and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. AL-57 functions as an ICAM-1 mimetic antibody that exhibits several key features of the ICAM-1/LFA-1 interaction. Not only do AL-57 and ICAM-1 both bind progressively better as LFA-1 affinity increases, they both require Mg2+ for binding.



Specifications
- Immunogen
- Human integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- Host Species
- Human
- Derivation
- Human
- Type
- Human scFv
- Specificity
- Human ITGAL
- Species Reactivity
- Human
- Clone
- AL-57
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ITGAL; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); CD11A; LFA-1; LFA1A; integrin alpha-L; LFA-1A; LFA-1 alpha; integrin gene promoter; CD11 antigen-like family member A; lymphocyte function-associated antigen 1; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide
- Gene ID
- 3683
- UniProt ID
- P20701
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
See other products for "Clone AL-57"
- CAT
- Product Name
See other products for "ITGAL"
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-024 | Anti-Human CD11A Recombinant Antibody (TAB-024) | Neut, ELISA, IF, IP, FuncS, FC, WB | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-108 | Anti-Human CD11a Recombinant Antibody (TAB-108) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG1 |
TAB-459CL | Mouse Anti-ITGAL Recombinant Antibody (TAB-459CL) | ELISA | Mouse IgG |
TAB-1579CL | Rat Anti-ITGAL Recombinant Antibody (TAB-1579CL) | Block | Rat IgG2a, κ |
TAB-1579CL-S(P) | Rat Anti-ITGAL Recombinant Antibody; scFv Fragment (TAB-1579CL-S(P)) | Block | Rat scFv |
TAB-1579CL-F(E) | Rat Anti-ITGAL Recombinant Antibody; Fab Fragment (TAB-1579CL-F(E)) | Block | Rat Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBW-159 | Human Anti-ITGAL Recombinant Antibody (clone AL-57); Fab Fragment | WB | Human Fab |
NS-018CN-F(E) | Human Anti-ITGAL Recombinant Antibody (clone MHM24); Fab Fragment | FC, ELISA | Human Fab |
HPAB-0487-WJ-F(E) | Mouse Anti-ITGAL Recombinant Antibody (clone S6F1); Fab Fragment | ELISA | Mouse Fab |
HPAB-S0088-YC-F(E) | Human Anti-ITGAL Recombinant Antibody (clone chMHM24); Fab Fragment | Inhib | Chimeric (mouse/human) Fab |
HPAB-S0089-YC-F(E) | Human Anti-ITGAL Recombinant Antibody (clone huMHM24); Fab Fragment | Inhib | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-755LC | Anti-human ITGAL Recombinant Antibody (Chimeric S6F1) (TAB-755LC) | ELISA | Chimeric antibody (mouse/human) |
TAB-755LC-S(P) | Anti-human ITGAL scFv Fragment (Chimeric S6F1) | ELISA | Chimeric antibody (mouse/human) |
TAB-755LC-F(E) | Anti-human ITGAL Fab Fragment (Chimeric S6F1) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1559CQ | Recombinant Mouse Anti-ITGAL Antibody (38) | FC, ICC, IF, IHC-Fr, IP, Neut | IgG2a |
NEUT-1563CQ | Recombinant Mouse Anti-ITGAL Antibody (CBL227) | FC, IHC, IP, Neut | IgG2a |
NEUT-1565CQ | Recombinant Rat Anti-Itgal Antibody (121/7) | FC, IP, Neut, WB | IgG2a |
NEUT-1568CQ | Recombinant Rat Anti-Itgal Antibody (I21/7) | Neut, FC, IHC, IHC-Fr, IP, ICC | IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1560CQ | Recombinant Mouse Anti-ITGAL Antibody (HI111) | FC, BL | IgG1, κ |
NEUT-1561CQ | Recombinant Mouse Anti-ITGAL Antibody (MEM-83) | BL, FC, FuncS, IP | IgG1 |
NEUT-1562CQ | Recombinant Mouse Anti-ITGAL Antibody (TS-1/22.1.1.13) | BL, FC | IgG1 |
NEUT-1564CQ | Recombinant Mouse Anti-ITGAL Antibody (R7-1) | BL, FC | IgG1 |
NEUT-1566CQ | Recombinant Rat Anti-Itgal Antibody (M17/4) | IP, IHC-Fr, FuncS, FC, BL | IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1878 | Hi-Affi™ Recombinant Rabbit Anti-ITGAL Monoclonal Antibody (DS1878AB) | BL, FC, ICC, IF, IHC-P, IP, WB | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-008CQ | Rat Anti-Mouse ITGAL Antibody (M17/4), APC Conjugated | FC, IHC, IP | Rat IgG2a, κ |
HPAB-S0088-YC | Human Anti-ITGAL Recombinant Antibody (clone chMHM24) | Inhib | Chimeric (mouse/human) IgG1 |
HPAB-S0089-YC | Human Anti-ITGAL Recombinant Antibody (clone huMHM24) | Inhib | Humanized IgG1 |
ZG-0880F | Mouse Anti-ITGAL Recombinant Antibody (clone OFYS) | FC | Mouse IgG2a |
VS3-FY771 | Recombinant Rabbit Anti-Itgal Antibody (clone R08-3I4) | WB, IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-018CN | Human Anti-ITGAL Recombinant Antibody (clone MHM24) | FC, ELISA, Inhib, FuncS | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-018CN-S(P) | Human Anti-ITGAL Recombinant Antibody (clone MHM24); scFv Fragment | FC, ELISA | Human scFv |
HPAB-0487-WJ-S(P) | Mouse Anti-ITGAL Recombinant Antibody (clone S6F1); scFv Fragment | ELISA | Mouse scFv |
HPAB-S0088-YC-S(P) | Human Anti-ITGAL Recombinant Antibody (clone chMHM24); scFv Fragment | Inhib | Mouse scFv |
HPAB-S0089-YC-S(P) | Human Anti-ITGAL Recombinant Antibody (clone huMHM24); scFv Fragment | Inhib | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-108 | Afuco™ Anti-ITGAL ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-108) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
AFC-TAB-024 | Afuco™ Anti-ITGAL ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-024) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0066SW | Recombinant Llama Anti-ITGAL Single Domain Antibody (MOB-0066SW) | ELISA, WB | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-FY45 | Human Anti-ITGAL scFv-Fc Chimera (VS-0425-FY45) | IA | Human IgG1, scFv-Fc |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-YC352 | Recombinant Anti-ITGAL Vesicular Antibody, EV Displayed (VS-0425-YC352) | ELISA, FC, Neut, Cell-uptake |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY3640 | Anti-ITGAL Immunohistochemistry Kit | IHC |
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