Recombinant monoclonal antibody 5B11 is a human monoclonal antibody that specifically binds to human integrin α5β1 and can be potentially used in the treatment of colon cancer and pancreatic cancer.
Figure 1 A bar chart showing the effect of inhibitory α5β1 antibodies on the attachment of endothelial cells to fibronectin, in the presence of 10 μL/mL L230.
Antibody treatments are indicated on the X-axis, and compared to a no treatment control. IgG1 control, 3C5 and 5B11 were used at 10 μg/ml and 25 μg/ml as indicated. The mean cell adhesion as measured by cell count is indicated on the Y-axis, together with the standard deviation of the mean (error bars).
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-719LC-F(E) | Anti-human Integrin α5β1 Fab Fragment (3C2.2A8) | ELISA, FC | Human antibody |
TAB-720LC-F(E) | Anti-human Integrin α5β1 Fab Fragment (3C5) | ELISA, FC | Human antibody |
TAB-721LC-F(E) | Anti-human Integrin α5β1 Fab Fragment (5B11) | ELISA, FC | Human antibody |
TAB-722LC-F(E) | Anti-human Integrin α5β1 Fab Fragment (MOR04055) | ELISA, FC | Human antibody |
TAB-723LC-F(E) | Anti-human Integrin α5β1 Fab Fragment (MOR04624) | ELISA, FC | Human antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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