Anti-Human LCN2 Recombinant Antibody (1-2322-455) (CAT#: TAB-486MZ)
This antibody is specific for glycosylated mammalian NGAL. The monoclonal antibody 1-2322-455 has the same affinity for both wild-type NGAL and mutant C87S NGAL.
Specific Inquiry
ELISA
Figure 1 shows the dose response curve for the 1-2322 cell line except that in this figure a negative control mAb with a matching negative control biotin-labeled antigen (NC mAb) was included along with to demonstrate the absence of nonspecific binding.
Symbols: (- ♦ -) NC mAb with NGAL-Bt; (- • -) mAb 1-2322-455 with NC Ag-Bt; (-■-) NC mAb with NC Ag-Bt; (- A-) mAb 1-2322-101 with NGAL-Bt; (- x - ) mAb 1- 2322-101 with NC Ag-Bt; (- * - ) mAb 1-2322-455 with NGAL-Bt.
ELISA
Figure 2 is an isotherm binding data graph for monoclonal antibody 1-2322-455 binding to different functional epitopes.
Symbols: (- o - , solid line) wild-type NGAL epitope; (- π - , solid line) NGAL epitope comprising S112A mutation; (- 0 - , long dashes line) NGAL epitope comprising Q117A mutation; (- x - , short dashes line) NGAL epitope comprising Hl 18A mutation; (- + - , dotted line) NGAL epitope comprising A118G mutation; (- Δ - , extra long dashes line) NGAL epitope comprising E147A mutation.
ELISA
Figure 3 shows the binding curves of anti-NGAL mAbs and NGAL (free NGAL concentration on the abscissa and fraction bound on the ordinate), and their calculated dissociation constants (Ka).
Symbols: (-•- ) mAb 903; (-■-) mAb 809; (-o- ) mAb 2322; (- T- ) mAb 181; (- Δ - ) mAb 269.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 1-2322-455
- Applications
- ELISA
- Related Disease
- Disease or disorder involving NGAL
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- LCN2; lipocalin 2; 24p3; MSFI; NGAL; neutrophil gelatinase-associated lipocalin; p25; lipocalin-2; oncogene 24p3; siderocalin LCN2; migration-stimulating factor inhibitor; 25 kDa alpha-2-microglobulin-related subunit of MMP-9
- Gene ID
- 3934
- UniProt ID
- P80188
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-614 | Recombinant Anti-human LCN2 Antibody | ELISA, WB, IF, FuncS | IgG |
| PABL-651 | Rat Anti-LCN2 Recombinant Antibody (clone mAb 1857) | WB | Rat IgG |
| MOB-1247MZ | Recombinant Mouse Anti-Rat LCN2 Antibody (clone 8) | ELISA, WB | Mouse antibody |
| ZG-0314C | Mouse Anti-LCN2 Recombinant Antibody (ZG-0314C) | ELISA | Mouse IgG |
| ZG-0148U | Mouse Anti-LCN2 Recombinant Antibody (clone 1A1B2) | ELISA, WB, IHC | Mouse IgG2b |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-614-F(E) | Recombinant Anti-human LCN2 Antibody Fab Fragment | WB, FACS, FuncS | Fab |
| MHH-614-F(E) | Recombinant Human Anti-human LCN2 Antibody Fab Fragment | WB, IHC, FuncS | Fab |
| PFBL-646 | Rat Anti-LCN2 Recombinant Antibody (clone mAb 1857); Fab Fragment | WB | Rat Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-614-S(P) | Recombinant Anti-human LCN2 Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| MHH-614-S(P) | Recombinant Human Anti-human LCN2 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| PSBL-646 | Rat Anti-LCN2 Recombinant Antibody (clone mAb 1857); scFv Fragment | WB | Rat scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-106 | Recombinant Anti-Human LCN2 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
Mouse Antibody
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0660MZ | Chicken Anti-Human Lipocalin-2/Neutrophil Gelatinase-Associated Lipocalin (NGAL) Polyclonal IgY | N/A | Chicken antibody |
| BRD-0661MZ | Chicken Anti-Human Lipocalin-2/Neutrophil Gelatinase-Associated Lipocalin (NGAL) complete IgY egg yolk Polyclonal IgY | N/A | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2024 | Hi-Affi™ Recombinant Rabbit Anti-LCN2 Monoclonal Antibody (DS2024AB) | WB, IHC, ICC | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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