Anti-Human MAG Recombinant Antibody (CAT#: TAB-510CL)

Recombinant Humanized monoclonal antibody expressed in CHO binding to Human MAG. TAB-510CL is an investigational drug intended to help repair brain injury, appears to be safe for patients with stroke, according to a phase I/II study. The drug is a monoclonal antibody that blocks myelin-associated glycoprotein to promote neurite outgrowth and protect oligodendrocytes. Serious adverse events were reported in 10 of 42 subjects and were distributed evenly among three treatment groups. Local investigators considered three of the serious adverse events to be potentially drug-related. No adverse event was fatal. One patient in the high-dose group had acute renal failure 18 days after stroke onset and a second stroke 38 days after stroke onset. One patient in the moderate-dose group had dysgeusia.


Specific Inquiry
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  • Purity:
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Derivation
  • Humanized
  • Type
  • Antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Stroke

Product Property

  • Purity
  • >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

Target

  • Alternative Names
  • MAG; myelin associated glycoprotein; GMA; S-MAG; SIGLEC4A; SIGLEC-4A; myelin-associated glycoprotein; sialic acid binding Ig-like lectin 4A; sialic acid-binding immunoglobulin-like lectin 4A

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "MAG"

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1720CQ Recombinant Mouse Anti-Mag Antibody (CBL528) WB, Neut IgG2a

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2121 Hi-Affi™ Recombinant Rabbit Anti-MAG Monoclonal Antibody (DS2121AB) WB, IP, FC IgG

Humanized Antibody

CAT Product Name Application Type
TAB-447CQ Anti-Human MAG Recombinant Antibody (Refanezumab) ELISA, IHC, FC, IP, IF, Inhib IgG1, κ

Recombinant Antibody

CAT Product Name Application Type
HPAB-0032-LS Human Anti-MAG Recombinant Antibody ELISA Chimeric (mouse/human) IgG1, κ
HPAB-0033-LS Human Anti-MAG Recombinant Antibody (clone BVh1/CVl1) ELISA, Neut Chimeric (mouse/human) IgG1, κ
HPAB-J0175-YC Mouse Anti-MAG Recombinant Antibody (clone muAP022/YC) ELISA Mouse IgG
HPAB-J0176-YC Human Anti-MAG Recombinant Antibody (clone chAP022/YC) ELISA Chimeric (mouse/human) IgG1
HPAB-J0177-YC Human Anti-MAG Recombinant Antibody (clone BVh3/CVI3) ELISA, FuncS Humanized (mouse/human) IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-447CQ Afuco™ Anti-MAG ADCC Recombinant Antibody (Refanezumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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