Recombinant Humanized monoclonal antibody expressed in CHO binding to Human MAG. TAB-510CL is an investigational drug intended to help repair brain injury, appears to be safe for patients with stroke, according to a phase I/II study. The drug is a monoclonal antibody that blocks myelin-associated glycoprotein to promote neurite outgrowth and protect oligodendrocytes. Serious adverse events were reported in 10 of 42 subjects and were distributed evenly among three treatment groups. Local investigators considered three of the serious adverse events to be potentially drug-related. No adverse event was fatal. One patient in the high-dose group had acute renal failure 18 days after stroke onset and a second stroke 38 days after stroke onset. One patient in the moderate-dose group had dysgeusia.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1720CQ | Recombinant Mouse Anti-Mag Antibody (CBL528) | WB, Neut | IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2121 | Hi-Affi™ Recombinant Rabbit Anti-MAG Monoclonal Antibody (DS2121AB) | WB, IP, FC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-447CQ | Anti-Human MAG Recombinant Antibody (Refanezumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0032-LS | Human Anti-MAG Recombinant Antibody | ELISA | Chimeric (mouse/human) IgG1, κ |
HPAB-0033-LS | Human Anti-MAG Recombinant Antibody (clone BVh1/CVl1) | ELISA, Neut | Chimeric (mouse/human) IgG1, κ |
HPAB-J0175-YC | Mouse Anti-MAG Recombinant Antibody (clone muAP022/YC) | ELISA | Mouse IgG |
HPAB-J0176-YC | Human Anti-MAG Recombinant Antibody (clone chAP022/YC) | ELISA | Chimeric (mouse/human) IgG1 |
HPAB-J0177-YC | Human Anti-MAG Recombinant Antibody (clone BVh3/CVI3) | ELISA, FuncS | Humanized (mouse/human) IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0032-LS-F(E) | Mouse Anti-MAG Recombinant Antibody; Fab Fragment | ELISA | Mouse Fab |
HPAB-0033-LS-F(E) | Human Anti-MAG Recombinant Antibody (clone BVh1/CVl1); Fab Fragment | ELISA, Neut | Human Fab |
HPAB-J0175-YC-F(E) | Mouse Anti-MAG Recombinant Antibody (clone muAP022/YC); Fab Fragment | ELISA | Mouse Fab |
HPAB-J0176-YC-F(E) | Human Anti-MAG Recombinant Antibody (clone chAP022/YC); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
HPAB-J0177-YC-F(E) | Human Anti-MAG Recombinant Antibody (clone BVh3/CVI3); Fab Fragment | ELISA | Humanized (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0032-LS-S(P) | Mouse Anti-MAG Recombinant Antibody; scFv Fragment | ELISA | Mouse scFv |
HPAB-0033-LS-S(P) | Human Anti-MAG Recombinant Antibody (clone BVh1/CVl1); scFv Fragment | ELISA, Neut | Human scFv |
HPAB-J0175-YC-S(P) | Mouse Anti-MAG Recombinant Antibody (clone muAP022/YC); scFv Fragment | ELISA | Mouse scFv |
HPAB-J0176-YC-S(P) | Human Anti-MAG Recombinant Antibody (clone chAP022/YC); scFv Fragment | ELISA | Mouse scFv |
HPAB-J0177-YC-S(P) | Human Anti-MAG Recombinant Antibody (clone BVh3/CVI3); scFv Fragment | ELISA | Humanized (mouse/human) scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-447CQ | Afuco™ Anti-MAG ADCC Recombinant Antibody (Refanezumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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