Afuco™ Anti-Human MC4R ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-495CL)
Anti-MC4R ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The autoantibodies against the melanocortin-4 receptor (MC4R) which is part of an important pathway regulating energy balance, are used for obese patients.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_9_3.jpg
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_9_3.jpg
Figure 2 Kidney
(Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_8_5.jpg
(Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_8_5.jpg
Figure 3 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_6_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_6_6.jpg
Figure 4 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_7_8.jpg
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16719/37246_A_7_8.jpg
Figure 5 RNA cell line category: Cell line enriched (fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166603-MC4R
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166603-MC4R
Specifications
- Host Species
- Mouse
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cachexia
Product Property
- Purity
- >95% by HPLC
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- MC4R; melanocortin 4 receptor; melanocortin receptor 4; MC4-R
- Gene ID
- 4160
- UniProt ID
- P32245
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MC4R"
Select a product category from the dropdown menu below to view related products.
Please select product type
Single Domain Antibody Products
IgG Antibody Products
IgM Antibody Products
Mouse Antibody Products
Rabbit Monoclonal Antibody Products
MHC Tetramer Products for Cancer
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1714-sdAb | Recombinant Anti-Human MC4R VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-495CL. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application:
Application: WB, ELISA, FuncS
Application: ELISA, SPR, Inhib, FuncS
Application: WB, ELISA, IF, FuncS, Apop, BA
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, IF, IP, FC, FuncS
-1.jpg)
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
