Afuco™ Anti-Human MMP13 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-510CL
Anti-MMP13 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies directed to the antigen MMP-13 are used for the treatment of diseases associated with the activity and/or overproduction of MMP-13. MMP-13 is expressed at elevated levels in cancers, degenerative bone diseases, and cardiovascular diseases. Inhibition of the biological activity of MMP-13 can delay the progression of symptoms caused by such diseases or conditions and other desired effects.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Glial cells Staining: Not detected Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_B_8_5.jpg
Normal Tissue
Figure 2 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_A_7_4.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_A_9_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_A_5_6.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (HaCaT, PC-3)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000137745-MMP13
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer; Degenerative Bone Diseases; Cardiovascular Disease
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- 4 °C, -20°C if preferred
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "MMP13"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2081z | Mouse Anti-MMP13 Recombinant Antibody (clone 19A7) | WB, ICC, IF, IHC | Mouse IgG2a |
| MOB-1941MZ | Recombinant Mouse Anti-Rat MMP13 Antibody (clone MJQDP JJE2), Biotin-Conjugated | ICC, IF, IP, WB | Mouse antibody |
| MRO-1009-CN | Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (JF0893) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-WK1856 | Recombinant Rabbit Anti-MMP13 Capture Antibody (clone R73-2Z-9) | ELISA | Rabbit IgG |
| VS3-WK1857 | Recombinant Rabbit Anti-MMP13 Detection Antibody (clone R78-6T-5) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0819CL | Anti-Human MMP13 Recombinant Antibody (14D10) | Inhib, ELISA | |
| TAB-0819CL-S(P) | Anti-Human MMP13 Recombinant Antibody scFv Fragment (14D10) | ELISA | |
| TAB-0819CL-F(E) | Anti-Human MMP13 Recombinant Antibody Fab Fragment (14D10) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0820CL | Human Anti-MMP13 Recombinant Antibody (TAB-0820CL) | ELISA, IHC | Human IgG |
| TAB-0820CL-S(P) | Human Anti-MMP13 Recombinant Antibody; scFv Fragment (TAB-0820CL-S(P)) | ELISA, IHC | Human scFv |
| TAB-0821CL-S(P) | Human Anti-MMP13 Recombinant Antibody; scFv Fragment (TAB-0821CL-S(P)) | ELISA, IHC | Human scFv |
| TAB-0820CL-F(E) | Human Anti-MMP13 Recombinant Antibody; Fab Fragment (TAB-0820CL-F(E)) | ELISA, IHC | Human Fab |
| TAB-0821CL-F(E) | Human Anti-MMP13 Recombinant Antibody; Fab Fragment (TAB-0821CL-F(E)) | ELISA, IHC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0369MZ | Chicken Anti-MMP13 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2250 | Hi-Affi™ Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (DS2250AB) | WB | IgG |
| MOR-4649 | Hi-Affi™ Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (TH162DS) | WB, IF, ICC, IHC-P, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4443 | Anti-MMP13 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4444 | Anti-Mouse MMP13 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4445 | Anti-Rat MMP13 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4446 | Anti-Rabbit MMP13 Immunohistochemistry Kit | IHC |
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