Recombinant Mouse Anti-MMP2 Antibody (CA719E3C)
CAT#: NEUT-1747CQ
This antibody is a mouse monoclonal antibody that binds specifically to MMP2, and it can neutralize the bioactivity of MMP2.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1939/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human stomach
Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1939/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human endometrium
Immunohistochemical staining of human endometrium shows moderate cytoplasmic positivity in stromal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2788/6952_B_5_3_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2788/6952_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2788/6952_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1939/7518_A_9_4.jpg
Normal Tissue
Figure 7 Gallbladder
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1939/7518_A_4_4.jpg
Normal Tissue
Figure 8 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2788/6952_A_8_5.jpg
Normal Tissue
Figure 9 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2788/6952_A_6_6.jpg
Normal Tissue
Figure 10 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1939/7518_A_8_8.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, hTERT-RPE1, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087245-MMP2
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Specifications
- Immunogen
- N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV
- Host Species
- Mouse
- Type
- IgG1
- Specificity
- Recognizes MMP2
- Species Reactivity
- Human, Mouse, Rat
- Clone
- CA719E3C
- Applications
- Used for immunoassay techniques such as: Inhibition; Immunohistochemistry; Western Blot; Immunocytochemistry
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G purified
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze-thaw cycles.
Target
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Related Diseases
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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|---|---|---|---|
| MOB-666-F(E) | Recombinant Anti-human MMP2 Antibody Fab Fragment | FC, Neut, Funcs | Fab |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-666-S(P) | Recombinant Anti-human MMP2 Antibody scFv Fragment | FC, WB, FuncS | scFv |
| MHH-666-S(P) | Recombinant Human Anti-human MMP2 Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0566CL | Mouse Anti-MMP2 Recombinant Antibody (TAB-0566CL) | Inhib | Mouse IgG |
| TAB-0566CL-S(P) | Mouse Anti-MMP2 Recombinant Antibody; scFv Fragment (TAB-0566CL-S(P)) | Inhib | Mouse scFv |
| TAB-0566CL-F(E) | Mouse Anti-MMP2 Recombinant Antibody; Fab Fragment (TAB-0566CL-F(E)) | Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0365MZ | Chicken Anti-MMP2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2253 | Hi-Affi™ Recombinant Rabbit Anti-MMP2 Monoclonal Antibody (DS2253AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2037-CN | Rabbit Anti-MMP2 Polyclonal Antibody (MRO-2037-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-FY939 | Recombinant Rabbit Anti-MMP2 Antibody (clone R06-4H3) | WB, ICC, IF | Rabbit IgG |
| VS3-WK1858 | Recombinant Rabbit Anti-Mouse MMP2 Capture Antibody (clone R35-1E-6) | ELISA | Rabbit IgG |
| VS3-WK1859 | Recombinant Rabbit Anti-Mouse MMP2 Detection Antibody (clone R36-7I-5) | ELISA | Rabbit IgG |
| VS13-YC734 | Rabbit Anti-MMP2 Recombinant Antibody (VS13-YC734) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY325 | Mouse Anti-NHP MMP2 Recombinant Antibody (clone 101) | WB, IHC, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1355 | Anti-MMP2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4452 | Anti-Mouse MMP2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4451 | Anti-Human MMP2 Immunohistochemistry Kit | IHC |
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