Mouse Anti-OSM Recombinant Antibody (clone 15E10) (CAT#: HPAB-0112-CN)
Antibody 15E10 is a therapeutic antibody that specifically binds to OSM, particularly hOSM, and modulates the interaction between OSM and gp130. 15E10 murine antibody was consistently more potent in the gp130 inhibition ELISA but had potency similar to 10D3 in the KB cell assay when human OSM was the target antigen. However, 15E10 murine antibody was much more potent than 10D3 against cynomolgus monkey OSM in both assays.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (HDLM-2, HL-60, HMC-1, Karpas-707, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000099985-OSM
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000099985-OSM
Specifications
- Immunogen
- Glycosylated human OSM
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2a, κ
- Species Reactivity
- Human, Monkey
- Clone
- 15E10
- Applications
- ELISA
- Related Disease
- Arthritic disease, e.g. rheumatoid arthritis and osteoarthritis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1474z | Mouse Anti-OSM Recombinant Antibody (clone 25C2) | WB, ELISA, IHC, Neut | Mouse IgG2a |
| MOB-2223MZ | Recombinant Mouse Anti-Human OSM Antibody (clone 28002.42) | ELISA, Neut, WB | Mouse antibody |
| HPAB-0113-CN | Mouse Anti-OSM Recombinant Antibody (clone 10D3) | ELISA | Mouse IgG1, κ |
| HPAB-0278CQ | Mouse Anti-OSM Recombinant Antibody (HPAB-0278CQ) | ELISA, IHC, FuncS, Inhib | Mouse IgG1, κ |
| HPAB-0279CQ | Human Anti-OSM Recombinant Antibody (HPAB-0279CQ) | ELISA, IHC, FuncS, Inhib | Human IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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