Mouse Anti-OSM Recombinant Antibody (clone 15E10); scFv Fragment (CAT#: HPAB-0112-CN-S(P))
Antibody 15E10 is a therapeutic antibody that specifically binds to OSM, particularly hOSM, and modulates the interaction between OSM and gp130. 15E10 murine antibody was consistently more potent in the gp130 inhibition ELISA but had potency similar to 10D3 in the KB cell assay when human OSM was the target antigen. However, 15E10 murine antibody was much more potent than 10D3 against cynomolgus monkey OSM in both assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (HDLM-2, HL-60, HMC-1, Karpas-707, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000099985-OSM
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000099985-OSM
Specifications
- Immunogen
- Glycosylated human OSM
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse scFv
- Species Reactivity
- Human, Monkey
- Clone
- 15E10
- Applications
- ELISA
- Related Disease
- Arthritic disease, e.g. rheumatoid arthritis and osteoarthritis
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1474z | Mouse Anti-OSM Recombinant Antibody (clone 25C2) | WB, ELISA, IHC, Neut | Mouse IgG2a |
| HPAB-0112-CN | Mouse Anti-OSM Recombinant Antibody (clone 15E10) | ELISA | Mouse IgG2a, κ |
| HPAB-0113-CN | Mouse Anti-OSM Recombinant Antibody (clone 10D3) | ELISA | Mouse IgG1, κ |
| HPAB-0114-CN | Human Anti-OSM Recombinant Antibody (clone B3L2) | ELISA | Humanized IgG |
| HPAB-0278CQ | Mouse Anti-OSM Recombinant Antibody (HPAB-0278CQ) | ELISA, IHC, FuncS, Inhib | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
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