Anti-P. falciparum AMA1 Recombinant Antibody (MRO-190CT) (CAT#: MRO-190CT)
Recombinant shark antibody specifically binds to Plasmodium falciparum AMA1, expressed in Chinese Hamster Ovary cells(CHO).
Specific Inquiry
ELISA
Figure 1 V(NAR)s 12Y-1 and 12Y-2 are specific for P. falciparum AMA1.
ELISA comparison of binding of affinity purified proteins 12Y-1 (black) and 12Y-2 (grey) to lysozyme, AMA1, -amylase, and Tom70.
Nuttall, S. D., Humberstone, K. S., Krishnan, U. V., Carmichael, J. A., Doughty, L., Hattarki, M., ... & Irving, R. A. (2004). Selection and affinity maturation of IgNAR variable domains targeting Plasmodium falciparum AMA1. PROTEINS: Structure, Function, and Bioinformatics, 55(1), 187-197.
SPR
Figure 2 V(NAR)s 12Y-1 and 12Y-2 are specific for P. falciparum AMA1.
BIAcore sensorgrams showing binding of varying concentrations (685, 342, 171, 85 nM) of monomeric VNAR protein 12Y-1 to immobilized AMA1 protein.
Nuttall, S. D., Humberstone, K. S., Krishnan, U. V., Carmichael, J. A., Doughty, L., Hattarki, M., ... & Irving, R. A. (2004). Selection and affinity maturation of IgNAR variable domains targeting Plasmodium falciparum AMA1. PROTEINS: Structure, Function, and Bioinformatics, 55(1), 187-197.
SPR
Figure 3 V(NAR)s 12Y-1 and 12Y-2 are specific for P. falciparum AMA1.
BIAcore sensorgrams showing binding of varying concentrations (685, 342, 171, 85 nM) of monomeric VNAR protein 12Y-1 to immobilized AMA1 protein.
Nuttall, S. D., Humberstone, K. S., Krishnan, U. V., Carmichael, J. A., Doughty, L., Hattarki, M., ... & Irving, R. A. (2004). Selection and affinity maturation of IgNAR variable domains targeting Plasmodium falciparum AMA1. PROTEINS: Structure, Function, and Bioinformatics, 55(1), 187-197.
Specifications
- Host Species
- Shark
- Species Reactivity
- P. falciparum
- Clone
- MRO-190CT
- Applications
- ELISA, SPR
Applications
- Application Notes
- The antibody was validated for ELISA, Surface plasmon resonance. For details, refer to Published Data.
Target
- Alternative Names
- apical membrane antigen 1; AMA1; AMA-1; Plasmodium falciparum; P. falciparum; Pf83; RMA-1; RMA1
- Gene ID
- 810891
- UniProt ID
- Q7KQK5
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-293 | Recombinant Rat Anti-P. Knowlesi AMA-1 Antibody (R31C2 ) | WB, BL, FuncS | IgG |
| PABW-097 | Recombinant Mouse Anti-P. falciparum AMA1 Antibody (1F9) | ELISA, BL | IgG |
| PABZ-098 | Recombinant Mouse Anti-P. vivax AMA-1 Antibody (F8.12.19) | IF | IgG |
| PABZ-148 | Recombinant Mouse Anti-P. vivax AMA1 Antibody (F8.12.19) | WB | IgG |
| MOB-2442CT | Recombinant Mouse anti-Caenorhabditis ama-1 Monoclonal antibody (3H22) | ICC/IF, ChIP, ChIP/Chip, WB, ELISA, IP, CHIPseq |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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