Recombinant Mouse Anti-P. vivax AMA1 Antibody (F8.12.19) (CAT#: PABZ-148)
Recombinant Mouse Antibody (F8.12.19) is capable of binding to P. vivax AMA1, expressed in Chinese Hamster Ovary cells (CHO). The monoclonal antibody recognises a discontinuous epitope located on domain III of the ectoplasmic region, the major component being a loop containing a cystine knot.
Specific Inquiry
IF
Figure 1 Pf3D7-AMA1 displays a type I TM topology at the plasma membrane of BHK-21 cells.
PfAMA1 transfected BHK-21 cells were subjected to IFA. Mouse MAb F8.12.19 recognizes extracellular PfAMA1 domain III that is accessible with or without permeabilization, whereas anti-Myc antibody labels the intracellular C-terminal Myc tag in permeabilized cells only.
Lamarque, M., Besteiro, S., Papoin, J., Roques, M., Vulliez-Le Normand, B., Morlon-Guyot, J., ... & Lebrun, M. (2011). The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites. PLoS pathogens, 7(2), e1001276.
Specifications
- Immunogen
- P. vivax Apical membrane antigen 1
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native P. vivax AMA1
- Species Reactivity
- P. vivax
- Clone
- F8.12.19
- Applications
- Can be useful in applications such as: Western Blot
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- AMA1; Apical membrane antigen 1
- UniProt ID
- O61130
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-293 | Recombinant Rat Anti-P. Knowlesi AMA-1 Antibody (R31C2 ) | WB, BL, FuncS | IgG |
| PABW-097 | Recombinant Mouse Anti-P. falciparum AMA1 Antibody (1F9) | ELISA, BL | IgG |
| PABZ-098 | Recombinant Mouse Anti-P. vivax AMA-1 Antibody (F8.12.19) | IF | IgG |
| PABL-397 | Human Anti-AMA1 Recombinant Antibody (PABL-397) | WB, ELISA, FuncS | Human IgG |
| MOB-2442CT | Recombinant Mouse anti-Caenorhabditis ama-1 Monoclonal antibody (3H22) | ICC/IF, ChIP, ChIP/Chip, WB, ELISA, IP, CHIPseq |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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