Anti-Human P2RX7 Therapeutical Antibody (CAT#: TAB-701CL)
Recombinant Human monoclonal antibody expressed in CHO binding to Human P2RX7. This product is against P2X7 receptor. It can be used in the treatment of a wide range of diseases including pain and neurodegenerative disorders.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows moderate positivity in neuropil.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_B_8_5_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows moderate positivity in neuropil.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_B_8_5_selected.jpg
Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows weak positivity in neuropil.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42013/103582_B_7_5_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows weak positivity in neuropil.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42013/103582_B_7_5_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_B_7_5.jpg
(Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_B_7_5.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_A_9_3.jpg
Figure 5 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_A_9_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_A_9_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_A_4_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_A_4_6.jpg
Figure 7 Skin
(Keratinocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_B_8_1.jpg
(Keratinocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_B_8_1.jpg
Figure 8 RNA cell line category: Cell line enhanced (Karpas-707, RPMI-8226, SK-MEL-30, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000089041-P2RX7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000089041-P2RX7
Specifications
- Host Species
- Human
- Type
- Single domain antibodies (Nbs)
- Species Reactivity
- Human
- Related Disease
- Pain; Neurodegenerative Disorders
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- P2RX7; purinergic receptor P2X, ligand gated ion channel, 7; P2X7; P2X purinoceptor 7; ATP receptor; P2Z receptor; P2X7 receptor; purinergic receptor P2X7 variant A; purinergic receptor P2X, ligand-gated ion channel, 7
- Gene ID
- 5027
- UniProt ID
- Q99572
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2843z | Mouse Anti-P2RX7 Recombinant Antibody (clone 24F9) | WB, ELISA, FC, IHC | Mouse IgG2b |
| HPAB-1590-FY | Mouse Anti-P2RX7 Recombinant Antibody (HPAB-1590-FY) | FC | Mouse IgG2a |
| VS3-WK121 | Mouse Anti-P2RX7 Recombinant Antibody (clone G1-D6) | WB, ELISA | Mouse IgG2b |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0916CL | Human Anti-P2RX7 Recombinant Antibody (TAB-0916CL) | WB, FC | Human IgG |
| TAB-0916CL-S(P) | Human Anti-P2RX7 Recombinant Antibody; scFv Fragment (TAB-0916CL-S(P)) | WB, FC | Human scFv |
| TAB-0916CL-F(E) | Human Anti-P2RX7 Recombinant Antibody; Fab Fragment (TAB-0916CL-F(E)) | WB, FC | Human Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0078CL-VHH | Anti-Human P2RX7 VHH Single Domain Antibody (1c81) | FC | Single domain antibody |
| TAB-0079CL-VHH | Llama Anti-P2RX7 Recombinant Antibody (TAB-0079CL-VHH) | FC | Llama VHH |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2565 | Hi-Affi™ Recombinant Rabbit Anti-P2RX7 Monoclonal Antibody (DS2565AB) | WB, IP, FC, ICC/IF | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1590-FY-F(E) | Mouse Anti-P2RX7 Recombinant Antibody; Fab Fragment (HPAB-1590-FY-F(E)) | Inhib | Mouse Fab |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1590-FY-S(P) | Mouse Anti-P2RX7 Recombinant Antibody; scFv Fragment (HPAB-1590-FY-S(P)) | Inhib | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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