Afuco™ Anti-Human PTK7 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-692CL
Anti-PTK7 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies target protein tyrosine kinase 7 (PTK7). They can use in preventing, treating or ameliorating hyperproliferative disorders and any expansion, recurrence, relapse or metastasis.
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Great for Cancer Research
The Afuco™ Anti-PTK7 ADCC antibody has been a groundbreaking addition to my research on breast cancer. Its enhanced ADCC capability provides clear results, particularly when assessing PTK7 expression in malignant cells. This specificity and potency accelerate our understanding of PTK7's role in cancer progression.
Enhances Immune Assay Outcomes
The increased ADCC activity of this antibody has significantly boosted the outcomes of our immune assays. The enhanced recruitment of effector cells has provided new insights into PTK7-associated immune interactions, opening doors to further discoveries in immune-oncology.
Perfect for Collaborative Projects
We've used this antibody collaboratively across institutions, and its performance remains consistent irrespective of differing lab environments. This consistency facilitates comparative studies and multi-center research initiatives.
Q&As
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What is the main target of the Anti-PTK7 ADCC Enhanced Antibody?
A: The main target of this antibody is protein tyrosine kinase 7 (PTK7). It is involved in numerous cellular processes and is particularly abundant in certain types of cancer cells. By targeting PTK7, this antibody aids in various research applications related to hyperproliferative disorders.
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Which types of cancer are related to PTK7 targets for this antibody?
A: Research suggests PTK7 is involved in cancers such as colorectal carcinoma, gastric cancer, and breast cancer. This antibody could help in studying these cancers due to its precise targeting capabilities.
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Why is PTK7 considered an inactive kinase?
A: PTK7 lacks key catalytic motifs typical of active kinases. Despite this, it plays essential roles as a cellular signaling co-factor, affecting cell proliferation and migration, which are processes of interest in cancer research.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "PTK7"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0356CT | Recombinant Mouse anti-Human PTK7 Monoclonal antibody (EML650) | WB | |
| HPAB-0027-LS | Human Anti-PTK7 Recombinant Antibody (HPAB-0027-LS) | ELISA, IB, FC, FuncS | Humanized IgG4 κ |
| ZG-0368F | Mouse Anti-PTK7 Recombinant Antibody (ZG-0368F) | WB, IHC, ELISA | Mouse IgG |
| VS3-XY1318 | Mouse Anti-PTK7 Recombinant Antibody (clone 4F9) | ELISA, WB, IHC | Mouse IgG1 |
| VS7-0425-WR716 | Mouse Anti-PTK7 Monoclonal Antibody (VS7-0425-WR716) | WB, IHC-P, IF, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0027-LS-F(E) | Human Anti-PTK7 Recombinant Antibody; Fab Fragment (HPAB-0027-LS-F(E)) | ELISA | Humanized Fab |
| HPAB-0028-LS-F(E) | Human Anti-PTK7 Recombinant Antibody; Fab Fragment (HPAB-0028-LS-F(E)) | ELISA, FC | Human Fab |
| HPAB-0029-LS-F(E) | Human Anti-PTK7 Recombinant Antibody; Fab Fragment (HPAB-0029-LS-F(E)) | ELISA, FC | Human Fab |
| HPAB-0030-LS-F(E) | Human Anti-PTK7 Recombinant Antibody; Fab Fragment (HPAB-0030-LS-F(E)) | ELISA, FC | Human Fab |
| HPAB-0031-LS-F(E) | Human Anti-PTK7 Recombinant Antibody; Fab Fragment (HPAB-0031-LS-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0027-LS-S(P) | Human Anti-PTK7 Recombinant Antibody; scFv Fragment (HPAB-0027-LS-S(P)) | ELISA | Humanized scFv |
| HPAB-0028-LS-S(P) | Human Anti-PTK7 Recombinant Antibody; scFv Fragment (HPAB-0028-LS-S(P)) | ELISA, FC | Human scFv |
| HPAB-0029-LS-S(P) | Human Anti-PTK7 Recombinant Antibody; scFv Fragment (HPAB-0029-LS-S(P)) | ELISA, FC | Human scFv |
| HPAB-0030-LS-S(P) | Human Anti-PTK7 Recombinant Antibody; scFv Fragment (HPAB-0030-LS-S(P)) | ELISA, FC | Human scFv |
| HPAB-0031-LS-S(P) | Human Anti-PTK7 Recombinant Antibody; scFv Fragment (HPAB-0031-LS-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY170 | Human Anti-PTK7 scFv-Fc Chimera (VS-0425-FY170) | WB, ELISA, IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC670 | Recombinant Anti-PTK7 Vesicular Antibody, EV Displayed (VS-0425-YC670) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5851 | Anti-PTK7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5852 | Anti-Rat PTK7 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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