Afuco™ Anti-Human PTPRB ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-694CL
Anti-PTPRB ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This antibody is expected to recognize both reported isoforms of protein tyrosine phosphatase, receptor type, beta polypeptide (PTPRB), which is critical in physiological and pathological events such as cell migration, adhesion and transformation.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67868/1717_A6_22_cr57f514fc87452_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human prostate
Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67868/1315_H7_2_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67868/1287_H7_1_blue_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/11835_B_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/11671_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/11671_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (EFO-21, hTERT-RPE1, HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000127329-PTPRB
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Specifications
- Host Species
- Rabbit
- Derivation
- Rabbit
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Diabetic macular edema
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- PTPRB; protein tyrosine phosphatase, receptor type, B; PTPB; HPTPB; VEPTP; HPTP-BETA; R-PTP-BETA; receptor-type tyrosine-protein phosphatase beta; VE-PTP; vascular endothelial protein tyrosine phosphatase; protein tyrosine phosphatase, receptor type, beta polypeptide
- Gene ID
- 5787
- UniProt ID
- P23467
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "PTPRB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3104z | Mouse Anti-PTPRB Recombinant Antibody (clone 7C10) | ICC, IF | Mouse IgG2a |
| MRO-1296-CN | Recombinant Mouse Anti-PTPRB Monoclonal Antibody (2-A2) | IF, IHC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-292CT | Human Anti-PTPRB Recombinant Antibody (TAB-292CT) | ELISA, FC | Human IgG |
| TAB-292CT-S(P) | Human Anti-PTPRB Recombinant Antibody; scFv Fragment (TAB-292CT-S(P)) | ELISA, FC | Human scFv |
| TAB-292CT-F(E) | Human Anti-PTPRB Recombinant Antibody; Fab Fragment (TAB-292CT-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS1-YJ199 | Mouse Anti-Ptprb Recombinant Antibody (clone 122.2) | IF, ICC, WB, IP | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC185 | Recombinant Anti-PTPRB Vesicular Antibody, EV Displayed (VS-0425-YC185) | ELISA, FC, Cell-uptake |
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