Anti-Human ROBO1 Recombinant Antibody (B2318C (binds to extracellular region of ROBO1)) (CAT#: TAB-0282CL)
The anti-ROBO1 antibody B2318C specifically binds to roundabout homolog 1, which has been identified as a molecule regulating the midline crossing of anxon and has been reported to work as a receptor for the Slit protein in subsequent studies. The specific antibody can be used for the diagnosis and treatment studies of cancer and a method for monitoring progression of hepatitis.
Specific Inquiry
Cyt
Figure 1 Complement-dependent cytotoxicity activity against ROBO1.
Calcein-labeled ROBO1_HEK293 cells and HEK293 cells (Mock) were incubated with 25% baby rabbit complement(Cedarlane) in the presence of 0 or 10 Ag/mL mAb B2318C.
Ito, H., Funahashi, S. I., Yamauchi, N., Shibahara, J., Midorikawa, Y., Kawai, S., ... & Iwanari, H. (2006). Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target. Clinical Cancer Research, 12(11), 3257-3264.
FC
Figure 2 Flow cytometricanalysis of recognition of ROBO1_HEK293 cells and liver cancer celllines (PLC/PRF/5, HepG2, HuH6, and HuH7) with the mAb B2318C.
y-axis, relative cell number; x-axis,fluorescent staining intensity on a logarithmic scale.
Ito, H., Funahashi, S. I., Yamauchi, N., Shibahara, J., Midorikawa, Y., Kawai, S., ... & Iwanari, H. (2006). Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target. Clinical Cancer Research, 12(11), 3257-3264.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- B2318C (binds to extracellular region of ROBO1)
- Applications
- Cyt, FC
- Related Disease
- Hepatitis
Applications
- Application Notes
- This antibody has been reported for use in Cytotoxicity and Flow Cytometry.
Target
- Alternative Names
- ROBO1; roundabout; axon guidance receptor; homolog 1 (Drosophila); SAX3; DUTT1; roundabout homolog 1; deleted in U twenty twenty
- Gene ID
- 6091
- UniProt ID
- Q9Y6N7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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See other products for "ROBO1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-346 | Mouse Anti-ROBO1 Recombinant Antibody (PABL-346) | WB, ELISA, FuncS | Mouse IgG2a kappa |
| MOB-1275MZ | Recombinant Mouse Anti-Human ROBO1 Antibody (clone 2G6) | WB | Mouse antibody |
| MRO-2166-CN | Rabbit Anti-ROBO1 Polyclonal Antibody (MRO-2166-CN) | IF, IHC | Rabbit IgG |
| PABJ-0064 | Mouse Anti-ROBO1 Recombinant Antibody (PABJ-0064) | ELISA, FuncS | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-346 | Mouse Anti-ROBO1 Recombinant Antibody; scFv Fragment (PSBL-346) | WB, ELISA, FuncS | Mouse scFv |
| PABJ-0064-S(P) | Mouse Anti-ROBO1 Recombinant Antibody; scFv Fragment (PABJ-0064-S(P)) | ELISA, FuncS | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-346 | Mouse Anti-ROBO1 Recombinant Antibody; Fab Fragment (PFBL-346) | WB, ELISA, FuncS | Mouse Fab |
| PABJ-0064-F(E) | Mouse Anti-ROBO1 Recombinant Antibody; Fab Fragment (PABJ-0064-F(E)) | ELISA, FuncS | Mouse Fab |
Mouse Antibody
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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