Afuco™ Anti-Human RTN4R ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-520CL)
Anti-RTN4R ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The monoclonal antibodies which bind to the Nogo-66 receptor have utility in the treatment of several states including but not limited to mammalian brain trauma, spinal cord injury, stroke, neurodegenerative diseases, and schizophrenia.
Specific Inquiry
Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12443/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12443/if_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (NB-4, REH, SCLC-21H, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000040608-RTN4R/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000040608-RTN4R/subcellular
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Brain Trauma; Spinal Cord Injury; Stroke; Neurodegenerative Diseases; Schizophrenia
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- 4°C or -20°C, avoid repeated freezing and thawing.
Target
- Alternative Names
- RTN4R; reticulon 4 receptor; NGR; NOGOR; reticulon-4 receptor; UNQ330/PRO526; nogo receptor; Nogo-66 receptor
- Gene ID
- 65078
- UniProt ID
- Q9BZR6
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Neuroscience Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-869 | Recombinant Anti-human RTN4R Antibody | WB, ELISA, IHC, FuncS | IgG |
| MHH-869 | Recombinant Human Anti-human RTN4R Antibody | IF, WB, FuncS | IgG |
| PABL-695 | Mouse Anti-RTN4R Recombinant Antibody (clone 1D9) | ELISA | Mouse IgG1 |
| HPAB-0738-YJ | Human Anti-RTN4R Recombinant Antibody (M5) | ELISA, WB, FC, IF, IP, ICC | Chimeric (rabbit/human) IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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