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    Human Anti-SOD1 Recombinant Antibody (TAB-470CT) (CAT#: TAB-470CT)

    This product is a recombinant human antibody that recognizes SOD1. It showed a strong binding preference for pathologically misfolded or aggregated SOD1. The epitope of this antibody is exposed upon SOD1 misfolding or aggregate formation. In direct ELISA assay, the EC₅₀ value of this antibody with 10 μM coating human SOD1 is 0.39 nM. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography. This antibody product could be used in the research of SOD1 targeted immunotherapy and SOD1 detection.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IHC staining of human cerebral cortex
    Figure 1 IHC staining of human cerebral cortex
    (Immunohistochemical staining of human cerebral cortex shows strong nuclear positivity in glial cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8670/ihc_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1401/30_D2_1_red_green.jpg
    Figure 3 IF staining of human cell line U-2 OS
    Figure 3 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1401/29_D2_1_red_green.jpg
    Figure 4 IF staining of human cell line U-251 MG
    Figure 4 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1401/31_D2_1_red_green.jpg
    Normal Tissue
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Glial cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Neuropil
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1401/4148_B_9_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Peripheral nerve/ganglion
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1401/4148_A_7_3.jpg
    Figure 7 Liver
    Figure 7 Liver
    (Cholangiocytes
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Hepatocytes
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1401/4148_A_8_4.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Cells in tubules
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1401/4148_A_7_5.jpg
    Figure 9 Testis
    Figure 9 Testis
    (Leydig cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Spermatogonia cells
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1401/4148_A_4_6.jpg
    Figure 10 Lymph node
    Figure 10 Lymph node
    (Non-germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1401/4148_A_8_8.jpg
    RNA Expression
    Figure 11 RNA cell line category: Low cell line specificity
    Figure 11 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142168-SOD1

    Specifications

    • Immunogen
    • Recombinant human SOD1
    • Host Species
    • Human
    • Type
    • Human antibody
    • Specificity
    • Human SOD1
    • Species Reactivity
    • Human
    • Applications
    • ELISA
    • Related Disease
    • Amyotrophic lateral sclerosis, Parkinson and Alzheimer

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • SOD1; superoxide dismutase 1; soluble; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer; superoxide dismutase [Cu-Zn]; SOD; soluble; indophenoloxidase A; Cu/Zn superoxide dismutase; superoxide dismutase; cystolic; epididymis secretory protein Li 44; anti-SOD1

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "SOD1"

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    CAT Product Name Application Type
    NAB-1217-VHH Recombinant Anti-human SOD1 VHH Single Domain Antibody Neut, ChiP, IP, FUNC Llama VHH
    TAB-465CT Anti-Human SOD1 Single Domain Antibody (TAB-465CT), Research Grade Biosimilar ELISA, WB, IHC, IP Single domain antibody
    MD-ZBF-YC020 Camelid Anti-SOD1 Recombinant Single Domain Antibody (MD-ZBF-YC020) WB, IP, IHC, ELISA Camelid VHH
    MD-ZBF-YC021 Camelid Anti-SOD1 Recombinant Single Domain Antibody (MD-ZBF-YC021) WB, IP, IHC, ELISA Camelid VHH
    MD-ZBF-YC022 Camelid Anti-SOD1 Recombinant Single Domain Antibody (MD-ZBF-YC022) WB, IP, IHC, ELISA Camelid VHH

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