Anti-Human TGF beta 2 Recombinant Antibody (TAB-100)
CAT#: TAB-100
Recombinant monoclonal antibody to TGF beta 2. It is a human monoclonal antibody and an immunosuppressive drug developed to reduce scarring after glaucoma drainage surgery.
Tested Data
Gene Expression
SDS-PAGE
Figure 1 Anti-TGF beta 2 Antibody (TAB-100) in SDS-PAGE
SDS-PAGE analysis of TAB-100 in non-reduced (lane 1) and β-mercaptoethanol-reduced (lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively. And non-reduced protein migrates as 130-180 kDa.
SEC-HPLC
Figure 2 Anti-TGF beta 2 Antibody (TAB-100) in HPLC
The purity of TAB-100 was greater than 95% as determined by SEC-HPLC.
Column: 3 µm, 7.8x300 nm
Mobile phase: 150 mM Sodium Phosphate Buffer, pH 7.3
Detection: UV280 nm
Injection: 10 µl
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Subcellular Location
Figure 1 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6134/2063_C8_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (EFO-21, hTERT-RPE1, U-2 OS)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000092969-TGFB2
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Specifications
- Immunogen
- An epitope of TGF beta 2 (Human).
- Host Species
- Human
- Derivation
- Human
- Type
- IgG4
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- ELISA, IP, FC, FuncS, Neut, IF, ICC
- Related Disease
- Glaucoma surgery
Product Property
- Purity
- >95.0% as determined by analysis by RP-HPLC.
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The TGFB2 antibody has been reported in applications of RT-PCR.
Target
- Alternative Names
- Lerdelimumab;Trabio;CAT-152;6B1;Anti-TGF-Beta-2;Trabio;Trabio;CAT-152;TGFB2;transforming growth factor, beta 2;transforming growth factor beta-2;G-TSF;cetermin;polyergin;BSC-1 cell growth inhibitor;glioblastoma-derived T-cell suppressor factor;TGF-beta2;M
- Gene ID
- 7042
- UniProt ID
- P61812
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(Creative Biolabs Cat# TAB-100, RRID: AB_3111804)
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Biosimilar Overview
Please refer to Lerdelimumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lerdelimumab.
Related Diseases
Inflammatory Bowel Diseases
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2017CQ | Rat Anti-Tgfb2 Recombinant Antibody (clone CBL883) | IHC, Neut, WB | Rat IgG2 |
| NEUT-2018CQ | Rat Anti-Tgfb2 Recombinant Antibody (clone CBL649) | Neut | Rat IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0662-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0662-YC) | ELISA, FuncS | Human IgG |
| HPAB-M0663-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0663-YC) | ELISA, FuncS | Human IgG |
| HPAB-0665YY | Human Anti-TGFB2 Recombinant Antibody (clone GDF11 Inh-2) | Inhib, ELISA, WB | Human IgG1 |
| VS3-CJ1082 | Mouse Anti-TGFB2 Recombinant Antibody (VS3-CJ1082) | WB, ICC, IHC | Mouse IgG1, κ |
| VS3-FY2893 | Mouse Anti-TGFB2 Recombinant Antibody (VS3-FY2893) | WB, IHC, ICC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0662-YC-S(P) | Human Anti-TGFB2 Recombinant Antibody; scFv Fragment (HPAB-M0662-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0663-YC-S(P) | Human Anti-TGFB2 Recombinant Antibody; scFv Fragment (HPAB-M0663-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0664-YC-S(P) | Human Anti-TGFB2 Recombinant Antibody; scFv Fragment (HPAB-M0664-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0665-YC-S(P) | Human Anti-TGFB2 Recombinant Antibody; scFv Fragment (HPAB-M0665-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0665YY-S(P) | Human Anti-TGFB2 Recombinant Antibody (clone GDF11 Inh-2); scFv Fragment | Inhib, ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0662-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0662-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0663-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0663-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0664-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0664-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0665-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0665-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0666-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0666-YC-F(E)) | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-100 | Afuco™ Anti-TGFB2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-100) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY188 | Mouse Anti-TGFB2 (clone 6A5) scFv-Fc Chimera | Neut, ELISA | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2277 | Anti-TGFB2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7211 | Anti-Mouse TGFB2 Immunohistochemistry Kit | IHC |
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