Afuco™ Anti-Human TGFA ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-582CL
Anti-TGFA ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibody capable of binding to transforming growth factor alpha (TGFA) can be used to treat cancer.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42297/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human rectum
Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42297/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42297/476_C8_2_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42297/94418_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42297/94418_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42297/94418_A_9_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42297/94418_A_9_5.jpg
Normal Tissue
Figure 8 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42297/94418_A_4_6.jpg
Normal Tissue
Figure 9 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42297/94418_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HBEC3-KT, OE19, RPTEC TERT1, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163235-TGFA
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Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
REVIEWS AND Q&AS
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Related Diseases
Non-small Cell Lung Cancer
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-122 | Mouse Anti-TGFA Recombinant Antibody (clone tAb2); Fab Fragment | WB, FuncS | Mouse Fab |
| HPAB-0544-CN-F(E) | Mouse Anti-TGFA Recombinant Antibody; Fab Fragment (HPAB-0544-CN-F(E)) | WB, ELISA, FC, IHC, IP, Neut | Mouse Fab |
| HPAB-0545-CN-F(E) | Mouse Anti-TGFA Recombinant Antibody; Fab Fragment (HPAB-0545-CN-F(E)) | WB, ELISA, FC, IHC, IP, Neut | Mouse Fab |
| HPAB-0546-CN-F(E) | Mouse Anti-TGFA Recombinant Antibody; Fab Fragment (HPAB-0546-CN-F(E)) | WB, ELISA, FC, IHC, IP, Neut | Mouse Fab |
| PFBC-538 | Human Anti-TGFA Recombinant Antibody Fab Fragment (PFBC-538) | ELISA, FC, Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-122 | Mouse Anti-TGFA Recombinant Antibody (clone tAb2); scFv Fragment | WB, FuncS | Mouse scFv |
| HPAB-0544-CN-S(P) | Mouse Anti-TGFA Recombinant Antibody; scFv Fragment (HPAB-0544-CN-S(P)) | WB, ELISA, FC, IHC, IP, Neut | Mouse scFv |
| HPAB-0545-CN-S(P) | Mouse Anti-TGFA Recombinant Antibody; scFv Fragment (HPAB-0545-CN-S(P)) | WB, ELISA, FC, IHC, IP, Neut | Mouse scFv |
| HPAB-0546-CN-S(P) | Mouse Anti-TGFA Recombinant Antibody; scFv Fragment (HPAB-0546-CN-S(P)) | WB, ELISA, FC, IHC, IP, Neut | Mouse scFv |
| PSBC-538 | Human Anti-TGFA Recombinant Antibody scFv Fragment (PSBC-538) | ELISA, FC, Neut | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0533CL | Mouse Anti-TGFA Recombinant Antibody (TAB-0533CL) | ELISA, Inhib | Mouse IgG |
| TAB-0533CL-S(P) | Mouse Anti-TGFA Recombinant Antibody; scFv Fragment (TAB-0533CL-S(P)) | ELISA, Inhib | Mouse scFv |
| TAB-0533CL-F(E) | Mouse Anti-TGFA Recombinant Antibody; Fab Fragment (TAB-0533CL-F(E)) | ELISA, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2017CT | Recombinant Mouse anti-Human TGFA Monoclonal antibody (Q/U2) | ELISA, ICC, IHC-Fr, IHC-P | |
| HPAB-0544-CN | Mouse Anti-TGFA Recombinant Antibody (HPAB-0544-CN) | WB, ELISA, FC, IHC, IP, Neut | Mouse IgG1, κ |
| HPAB-0545-CN | Mouse Anti-TGFA Recombinant Antibody (HPAB-0545-CN) | WB, ELISA, FC, IHC, IP, Neut | Mouse IgG1, κ |
| HPAB-0546-CN | Mouse Anti-TGFA Recombinant Antibody (HPAB-0546-CN) | WB, ELISA, FC, IHC, IP, Neut | Mouse IgG2a, κ |
| VS3-FY1445 | Recombinant Rabbit Anti-TGFA Antibody (clone R07-6J8) | WB, IHC-P, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY251 | AbPlus™ Anti-TGFA Magnetic Beads (VS-0424-XY251) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC553 | Recombinant Anti-TGFA Vesicular Antibody, EV Displayed (VS-0425-YC553) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7205 | Anti-TGFA Immunohistochemistry Kit | IHC | |
| VS-0525-XY7206 | Anti-Mouse TGFA Immunohistochemistry Kit | IHC | |
| VS-0525-XY7207 | Anti-Human TGFA Immunohistochemistry Kit | IHC |
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