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    Afuco™ Anti-Human TNFRSF4 ADCC Recombinant Antibody (MEDI6469), ADCC Enhanced (CAT#: AFC-609CL)

    Anti-TNFRSF4 ADCC Enhanced Antibody (MEDI6469) is an ADCC enhanced antibody produced by our Afuco™ platform. MEDI6469 is a murine (mouse)-based antibody that binds to and activates a protein in humans called OX40. Because OX40 helps activate the immune system, it is hoped that it will encourage the immune system to recognize and eliminate cancer cells.

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 High expression in lymph node.
    Figure 1 High expression in lymph node.
    (Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16128/35587_A_7_8.jpg
    Figure 2 Tonsil
    Figure 2 Tonsil
    (Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16128/35587_A_6_8.jpg
    RNA Expression
    Figure 3 RNA cell line category: Group enriched (MOLT-4, NB-4)
    Figure 3 RNA cell line category: Group enriched (MOLT-4, NB-4)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186827-TNFRSF4

    Specifications

    • Host Species
    • Mouse
    • Derivation
    • Mouse
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Applications
    • FuncS
    • Related Disease
    • Cancer; Melanoma

    Product Property

    • Purity
    • >97%, by SDS-PAGE under reducing conditions
    • Storage
    • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

    Applications

    • Application Notes
    • The antibody was validated for Function Assay. For details, refer to Published Data.

    Target

    • Alternative Names
    • TNFRSF4; tumor necrosis factor receptor superfamily, member 4; OX40; ACT35; CD134; IMD16; TXGP1L; tumor necrosis factor receptor superfamily member 4; OX40 antigen; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 homologue; OX40L receptor; OX40 cell surface antigen; lymphoid activation antigene ACT35; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1 receptor

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    TAB-633CL Mouse Anti-TNFRSF4 Recombinant Antibody (TAB-633CL) ELISA Mouse IgG
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