Rabbit Anti-TNFSF12 Recombinant Antibody (clone YC151); Fab Fragment (CAT#: PFBL-725)
Recombinant Rabbit Antibody Fab Fragment is specific to TNFSF12, expressed in Chinese Hamster Ovary cells (CHO). This Fab fragment could bind human TWEAK, neutralize TWEAK-Fn14 interaction and inhibit TWEAK-induced IL-8 secretion in A375 melanoma cells.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35984/1698_F1_5_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35984/1698_F1_5_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows distinct positivity in a subset of non-germinal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52967/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows distinct positivity in a subset of non-germinal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52967/ihc_selected.jpg
Figure 3 RNA cell line category: Cell line enhanced (ASC TERT1, BJ hTERT+, HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000239697-TNFSF12
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000239697-TNFSF12
Specifications
- Immunogen
- Human tumor necrosis factor (ligand) superfamily, member 12
- Host Species
- Rabbit
- Type
- Rabbit Fab
- Specificity
- Human TNFSF12
- Species Reactivity
- Human
- Clone
- YC151
- Applications
- ELISA, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; APO3L; DR3LG; TWEAK; tumor necrosis factor ligand superfamily member 12; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis
- Gene ID
- 8742
- UniProt ID
- O43508
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2051z | Mouse Anti-TNFSF12 Recombinant Antibody (clone 32B8) | FC, FuncS | Mouse IgG3 |
| PABL-354 | Human Anti-TNFSF12 Recombinant Antibody (clone YC155) | ELISA, Neut, FuncS | Human IgG |
| PABL-732 | Rabbit Anti-TNFSF12 Recombinant Antibody (clone YC150) | ELISA, Neut | Rabbit IgG |
| MOB-2131CT | Recombinant Mouse anti-Human TNFSF12 Monoclonal antibody (EML2038) | WB | |
| HPAB-1624-FY | Human Anti-TNFSF12 Recombinant Antibody (HPAB-1624-FY) | WB, ELISA, IF | Humanized IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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