Afuco™ Anti-TNFSF12 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-178) (CAT#: AFC-TAB-178)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to TWEAK receptor. It is a humanized monoclonal antibody designed for the treatment of cancers.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35984/1698_F1_5_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35984/1698_F1_5_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows distinct positivity in a subset of non-germinal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52967/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows distinct positivity in a subset of non-germinal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52967/ihc_selected.jpg
Figure 3 RNA cell line category: Cell line enhanced (ASC TERT1, BJ hTERT+, HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000239697-TNFSF12
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000239697-TNFSF12
Specifications
- Immunogen
- Human Fn14 transfected P815.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, FC, IP, FuncS, IF, Neut
- Conjugate
- Unconjugated
- Generic Name
- Enavatuzumab
- Related Disease
- Solid tumors
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand superfamily member 12; APO3L; DR3LG; TWEAK; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis;
- Gene ID
- 8742
- UniProt ID
- O43508
Related Resources
Please refer to Enavatuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Enavatuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Mouse Antibody Products
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Blocking Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2051z | Mouse Anti-TNFSF12 Recombinant Antibody (clone 32B8) | FC, FuncS | Mouse IgG3 |
| PABL-354 | Human Anti-TNFSF12 Recombinant Antibody (clone YC155) | ELISA, Neut, FuncS | Human IgG |
| HPAB-0947-FY | Human Anti-TNFSF12 Recombinant Antibody (clone 301) | ELISA | Chimeric (rabbit/human) IgG1 |
| HPAB-0948-FY | Human Anti-TNFSF12 Recombinant Antibody (clone 304) | ELISA | Chimeric (rabbit/human) IgG1 |
| HPAB-0949-FY | Human Anti-TNFSF12 Recombinant Antibody (clone 305) | ELISA | Chimeric (rabbit/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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