Afuco™ Anti-Human TNFSF15 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-616CL
Anti-TNFSF15 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibody which binds specifically to TL1a is used in several immune-mediated conditions, such as, experimental autoimmune encephalomyelitis (EAE; a model of multiple sclerosis), colitis, inflammatory bowel disease, asthma and arthritis. TLla has also been shown to promote formation of foam cells and atherosclerotic plaques.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm & nuclear membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46522/1383_A7_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human esophagus
Immunohistochemical staining of human esophagus shows strong membranous positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12948/29318_B_4_1_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12948/29318_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12948/29318_A_8_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12948/29318_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12948/29318_A_6_6.jpg
Normal Tissue
Figure 7 Skin
Epidermal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12948/29318_B_5_8.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12948/29318_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000181634-TNFSF15
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Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Experimental Autoimmune Encephalomyelitis; Inflammatory Bowel Disease
Product Property
- Purity
- >95% by HPLC
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- TNFSF15; tumor necrosis factor (ligand) superfamily, member 15; TL1; TL1A; VEGI; VEGI192A; tumor necrosis factor ligand superfamily member 15; TNF superfamily ligand TL1A; TNF ligand-related molecule 1; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor-192A
- Gene ID
- 9966
- UniProt ID
- O95150
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "TNFSF15"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-334CQ | Mouse Anti-TNFSF15 Recombinant Antibody (TAB-334CQ) | ELISA | Mouse IgG2a, κ |
| TAB-335CQ | Mouse Anti-TNFSF15 Recombinant Antibody (TAB-335CQ) | ELISA, FC, BL | Mouse IgG2a, κ |
| TAB-338CQ | Hamster Anti-TNFSF15 Recombinant Antibody (TAB-338CQ) | ELISA, FC, Block | Hamster IgG |
| TAB-339CQ | Hamster Anti-TNFSF15 Recombinant Antibody (TAB-339CQ) | ELISA, FC, BL | Hamster IgG |
| TAB-346CQ | Mouse Anti-TNFSF15 Recombinant Antibody (TAB-346CQ) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-336CQ | Human Anti-TNFSF15 Recombinant Antibody (TAB-336CQ) | ELISA, FC, BL | Humanized antibody |
| TAB-337CQ | Human Anti-TNFSF15 Recombinant Antibody (TAB-337CQ) | ELISA, FC, BL | Humanized antibody |
| TAB-347CQ | Human Anti-TNFSF15 Recombinant Antibody (TAB-347CQ) | Block, ELISA, FC, FuncS | Humanized IgG |
| TAB-336CQ-F(E) | Human Anti-TNFSF15 Recombinant Antibody; Fab Fragment (TAB-336CQ-F(E)) | ELISA, FC, BL | Humanized Fab |
| TAB-337CQ-F(E) | Human Anti-TNFSF15 Recombinant Antibody; Fab Fragment (TAB-337CQ-F(E)) | ELISA, FC, BL | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-340CQ | Human Anti-TNFSF15 Recombinant Antibody (TAB-340CQ) | ELISA, FC, Neut | Human IgG1, κ |
| TAB-341CQ | Human Anti-TNFSF15 Recombinant Antibody (TAB-341CQ) | ELISA, FC, Inhib | Human IgG1, κ |
| TAB-342CQ | Human Anti-TNFSF15 Recombinant Antibody (TAB-342CQ) | ELISA, FC, Neut | Human IgG1, κ |
| TAB-343CQ | Human Anti-TNFSF15 Recombinant Antibody (TAB-343CQ) | ELISA | Human IgG1, κ |
| TAB-344CQ | Human Anti-TNFSF15 Recombinant Antibody (TAB-344CQ) | ELISA, FC, Neut | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2187CQ | Rat Anti-Tnfsf15 Recombinant Antibody (clone CBL658) | Neut | Rat IgG1 |
| NEUT-2188CQ | Rat Anti-Tnfsf15 Recombinant Antibody (clone CBL204) | WB, Neut | Rat IgG1 |
| NEUT-2189CQ | Rabbit Anti-TNFSF15 Recombinant Antibody (NEUT-2189CQ) | Neut, WB, IHC | Rabbit IgG |
| NEUT-2190CQ | Rat Anti-TNFSF15 Recombinant Antibody (clone CBL610) | WB, Neut | Rat IgG1 |
| NEUT-2191CQ | Rabbit Anti-TNFSF15 Recombinant Antibody (clone CBL722) | WB, Neut | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0011-WJ-S(P) | Human Anti-TNFSF15 Recombinant Antibody; scFv Fragment (HPAB-0011-WJ-S(P)) | ELISA, Neut | Human scFv |
| HPAB-0831-FY-F(E) | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-0831-FY-F(E)); Fab Fragment | Inhib, ELISA | Mouse Fab |
| HPAB-0832-FY-F(E) | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-0832-FY-F(E)); Fab Fragment | Inhib, ELISA | Mouse Fab |
| HPAB-0833-FY-F(E) | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-0833-FY-F(E)); Fab Fragment | Inhib, ELISA | Mouse Fab |
| HPAB-1443-FY-F(E) | Mouse Anti-TNFSF15 Recombinant Antibody; Fab Fragment (HPAB-1443-FY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0831-FY-S(P) | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-0831-FY-S(P)); scFv Fragment | Inhib, ELISA | Mouse scFv |
| HPAB-0832-FY-S(P) | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-0832-FY-S(P)); scFv Fragment | Inhib, ELISA | Mouse scFv |
| HPAB-0833-FY-S(P) | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-0833-FY-S(P)); scFv Fragment | Inhib, ELISA | Mouse scFv |
| HPAB-0834-FY-S(P) | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-0834-FY-S(P)); scFv Fragment | Inhib, ELISA | Mouse scFv |
| HPAB-1443-FY-S(P) | Mouse Anti-TNFSF15 Recombinant Antibody; scFv Fragment (HPAB-1443-FY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1443-FY | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-1443-FY) | ELISA | Mouse IgG |
| HPAB-1444-FY | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-1444-FY) | ELISA | Mouse IgG |
| HPAB-1445-FY | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-1445-FY) | ELISA | Mouse IgG |
| HPAB-1446-FY | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-1446-FY) | ELISA, Block | Mouse IgG |
| HPAB-1447-FY | Mouse Anti-TNFSF15 Recombinant Antibody (HPAB-1447-FY) | ELISA, Block | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7395 | Anti-TNFSF15 Immunohistochemistry Kit | IHC |
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