Anti-Human TNFSF4 Therapeutic Single Domain Antibody (CAT#: TAB-642CL)
Recombinant Humanized monoclonal antibody expressed in E. coli binding to Human TNFSF4. The antibodiess against ox40l can be used for prophylactic, therapeutic or diagnostic purposes, such as for the treatment of inflammatory disease and disorder such as such as asthma, allergic asthma, chronic colitis, Crohn's disease, inflammatory bowel disease, and arthrosclerosis.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/1331_F5_1_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/1331_F5_1_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_4_8_selected.jpg
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_4_8_selected.jpg
Figure 3 Duodenum
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_2.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_2.jpg
Figure 4 Colon
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_9_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_9_3.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_6_6.jpg
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, HHSteC, HUVEC TERT2, LHCN-M2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117586-TNFSF4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117586-TNFSF4
Specifications
- Derivation
- Humanized
- Type
- Single Domain Antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Disease
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
- Alternative Names
- TNFSF4; tumor necrosis factor (ligand) superfamily, member 4; GP34; CD252; OX4OL; TXGP1; CD134L; OX-40L; tumor necrosis factor ligand superfamily member 4; CD134 ligand; glycoprotein Gp34; OX40 antigen ligand; tax-transcriptionally activated glycoprotein
- Gene ID
- 7292
- UniProt ID
- P23510
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TNFSF4"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1645z | Mouse Anti-TNFSF4 Recombinant Antibody (clone 28F11) | FC, IHC, Neut | Mouse IgG1 |
| HPAB-0144-CN | Mouse Anti-TNFSF4 Recombinant Antibody (HPAB-0144-CN) | ELISA, FC | Mouse IgG |
| HPAB-0145-CN | Mouse Anti-TNFSF4 Recombinant Antibody (HPAB-0145-CN) | ELISA, FC | Mouse IgG |
| HPAB-0146-CN | Human Anti-TNFSF4 Recombinant Antibody (HPAB-0146-CN) | ELISA, FC | Human IgG1, κ |
| HPAB-0147-CN | Human Anti-TNFSF4 Recombinant Antibody (HPAB-0147-CN) | ELISA, FC | Human IgG1, κ |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-102 | Recombinant Anti-human TNFSF4 VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| HPAB-0617-CN | Llama Anti-TNFSF4 Recombinant Single Domain Antibody (HPAB-0617-CN) | ELISA, FC, Block | Llama VHH |
| HPAB-0618-CN | Llama Anti-TNFSF4 Recombinant Single Domain Antibody (HPAB-0618-CN) | ELISA, FC, Block | Llama VHH |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0894CL | Mouse Anti-TNFSF4 Recombinant Antibody (TAB-0894CL) | ELISA | Mouse IgG |
| TAB-0895CL | Mouse Anti-TNFSF4 Recombinant Antibody (TAB-0895CL) | ELISA | Mouse IgG2b |
| TAB-0896CL | Mouse Anti-TNFSF4 Recombinant Antibody (TAB-0896CL) | ELISA | Mouse IgG |
| TAB-0270CL-S(P) | Anti-Human TNFSF4 Recombinant Antibody scFv Fragment (W66) | ELISA, WB | |
| TAB-0894CL-F(E) | Mouse Anti-TNFSF4 Recombinant Antibody; Fab Fragment (TAB-0894CL-F(E)) | ELISA | Mouse Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0897CL-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (TAB-0897CL-S(P)) | FC | Human scFv |
| TAB-0898CL-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (TAB-0898CL-S(P)) | FC | Human scFv |
| TAB-0899CL-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (TAB-0899CL-S(P)) | FC | Human scFv |
| TAB-0900CL-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (TAB-0900CL-S(P)) | FC | Human scFv |
| TAB-0901CL-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (TAB-0901CL-S(P)) | ELISA | Human scFv |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2198CQ | Rat Anti-Tnfsf4 Recombinant Antibody (clone mAb0834) | Block, FC, IHC-Fr | Rat IgG2 |
| NEUT-2199CQ | Rat Anti-Tnfsf4 Recombinant Antibody (clone RM134L) | Block, FC, IP | Rat IgG2b |
| NEUT-2201CQ | Mouse Anti-Tnfsf4 Recombinant Antibody (clone OX-89) | IHC-Fr, FC, Block | Mouse IgG2a, κ |
| NEUT-2204CQ | Mouse Anti-TNFSF4 Recombinant Antibody (clone R4930) | FC, Block | Mouse IgG, κ |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2200CQ | Rat Anti-Tnfsf4 Recombinant Antibody (clone CBL346) | Neut, WB | Rat IgG2a |
| NEUT-2202CQ | Mouse Anti-TNFSF4 Recombinant Antibody (clone CBL569) | FC, CyTOF, ICC, Neut | Mouse IgG1 |
| NEUT-2203CQ | Mouse Anti-TNFSF4 Recombinant Antibody (clone MM0505-8S23) | FC, IHC, IHC-Fr, CyTOF, Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3622 | Rabbit Anti-TNFSF4 Recombinant Antibody (clone DS3622AB) | WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0144-CN-S(P) | Mouse Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0144-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0145-CN-S(P) | Mouse Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0145-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0146-CN-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0146-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0147-CN-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0147-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0148-CN-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0148-CN-S(P)) | ELISA, FC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0144-CN-F(E) | Mouse Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0144-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0145-CN-F(E) | Mouse Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0145-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0146-CN-F(E) | Human Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0146-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0147-CN-F(E) | Human Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0147-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0148-CN-F(E) | Human Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0148-CN-F(E)) | ELISA, FC | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-223 | Afuco™ Anti-TNFSF4 ADCC Recombinant Antibody (Oxelumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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