Anti-Human TNFSF4 Single Domain Antibody, Research Grade Biosimilar (CAT#: TAB-642CL)
Recombinant Humanized monoclonal antibody expressed in E. coli binding to Human TNFSF4. The antibodiess against ox40l can be used for prophylactic, therapeutic or diagnostic purposes, such as for the treatment of inflammatory disease and disorder such as such as asthma, allergic asthma, chronic colitis, Crohn's disease, inflammatory bowel disease, and arthrosclerosis.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/1331_F5_1_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/1331_F5_1_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_4_8_selected.jpg
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_4_8_selected.jpg
Figure 3 Duodenum
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_2.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_2.jpg
Figure 4 Colon
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_9_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_9_3.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_6_6.jpg
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, HHSteC, HUVEC TERT2, LHCN-M2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117586-TNFSF4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117586-TNFSF4
Specifications
- Derivation
- Humanized
- Type
- Single Domain Antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Disease
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
- Alternative Names
- TNFSF4; tumor necrosis factor (ligand) superfamily, member 4; GP34; CD252; OX4OL; TXGP1; CD134L; OX-40L; tumor necrosis factor ligand superfamily member 4; CD134 ligand; glycoprotein Gp34; OX40 antigen ligand; tax-transcriptionally activated glycoprotein
- Gene ID
- 7292
- UniProt ID
- P23510
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1645z | Mouse Anti-TNFSF4 Recombinant Antibody (clone 28F11) | FC, IHC, Neut | Mouse IgG1 |
| MOB-0429ZL | Mouse Anti-TNFSF4 Recombinant Antibody (clone YC164) | Neut, FC, IHC | Mouse IgG1 |
| HPAB-0144-CN | Mouse Anti-TNFSF4 Recombinant Antibody (HPAB-0144-CN) | ELISA, FC | Mouse IgG |
| HPAB-0145-CN | Mouse Anti-TNFSF4 Recombinant Antibody (HPAB-0145-CN) | ELISA, FC | Mouse IgG |
| HPAB-0146-CN | Human Anti-TNFSF4 Recombinant Antibody (HPAB-0146-CN) | ELISA, FC | Human IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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