Anti-Human Tau Recombinant Antibody (pS396/pS404_1) (CAT#: TAB-532CT)
Recombinant monoclonal antibody specifically binds to phospho-tau with high affinity. This antibody can be potentially used in treating Alzheimer's Disease.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Expression and binding activity of chimeric IgG molecules converted from scFv.
Western blot analysis of chimeric IgG molecules convertedfrom scFv clones pT231/pS235_1, pS396/pS404_1, and pT212/pS214_1, respectively. The heavy and light chains for each IgG are indicated by arrows.
Shih, H. H., Tu, C., Cao, W., Klein, A., Ramsey, R., Fennell, B. J., ... & Laxmanan, S. (2012). An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition. Journal of Biological Chemistry, 287(53), 44425-44434.
Figure 2 Expression and binding activity of chimeric IgG molecules converted from scFv.
ELISA analysis of each purified IgG molecule for binding to the phosphopeptide, non-phosphopeptide, and scrambled (Scr) peptide.
Shih, H. H., Tu, C., Cao, W., Klein, A., Ramsey, R., Fennell, B. J., ... & Laxmanan, S. (2012). An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition. Journal of Biological Chemistry, 287(53), 44425-44434.
Specifications
- Host Species
- Chicken
- Derivation
- Phage display library
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- pS396/pS404_1
- Applications
- WB, ELISA
- Related Disease
- Alzheimer's Disease
Applications
- Application Notes
- This antibody has been reported for use in Western Blot and Enzyme-Linked Immunosorbent Assay.
Target
- Alternative Names
- TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
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