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Tau

Anti-Tau Products
- Human Anti-Tau Recombinant Antibody (MOB-0054SW) (MOB-0054SW)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG4
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, IF, FuncS
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-535CT-F(E)) (TAB-535CT-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, IHC
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: WB, ELISA, IP, IHC, Neut
- Human Anti-Tau Recombinant Antibody; scFv Fragment (TAB-527CT-S(P)) (TAB-527CT-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, IHC
- Mouse Anti-pan Tau Recombinant Antibody (clone tau5) (VS-0623-WK90)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, IF, FuncS
- Mouse Anti-Tau Recombinant Antibody (clone Tau-5) (FAMAB-1513CQ)
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- Species Reactivity: Rat, Sheep, Human, Mouse
- Type: Mouse IgG1
- Application: EM, IF
- Mouse Anti-Tau Recombinant Antibody (clone MHT2) (FAMAB-0352WJ)
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB, IHC
- Recombinant Anti-Tau Antibody (MOB-951)
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- Derivation: Mouse
- Type: IgG
- Application: ELISA, WB, IP, FuncS
- Recombinant Human Anti-Tau Antibody (MHH-951)
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- Derivation: Human
- Type: IgG
- Application: WB, Neut, FuncS
- Mouse Anti-Tau Recombinant Antibody (PABS-0209) (PABS-0209)
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- Derivation: Hybridoma cell line
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB, DB, IHC
- Mouse Anti-Tau Antibody (clone MHT2), mRNA (FAMAB-0352WJ-mRNA)
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- Species Reactivity: Human
- Mouse Anti-Tau Recombinant Antibody (clone Tau5) (HPAB-S0178-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-Tau Recombinant Antibody (HPAB-2569LY) (HPAB-2569LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IP, WB
- Mouse Anti-Tau Recombinant Antibody (HPAB-2570LY) (HPAB-2570LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IP, WB
- Human Anti-Tau Recombinant Antibody (HPAB-2563LY) (HPAB-2563LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: WB, IHC, ELISA
- Human Anti-Tau Recombinant Antibody (HPAB-2564LY) (HPAB-2564LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: WB
- Human Anti-Tau Recombinant Antibody (HPAB-2565LY) (HPAB-2565LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: WB
- Rabbit Anti-Tau Recombinant Antibody (HPAB-2566LY) (HPAB-2566LY)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
- Mouse Anti-Tau Recombinant Antibody (HPAB-2567LY) (HPAB-2567LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IP, WB
- Mouse Anti-Tau Recombinant Antibody (HPAB-2568LY) (HPAB-2568LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IP, WB
- Human Anti-Tau Recombinant Antibody (HPAB-2561LY) (HPAB-2561LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: WB, IHC, ELISA
- Human Anti-Tau Recombinant Antibody (HPAB-2562LY) (HPAB-2562LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: WB, IHC, ELISA
- Mouse Anti-Tau Antibody (clone Tau-5), mRNA (FAMAB-1513CQ-mRNA)
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- Species Reactivity: Rat, Sheep, Human, Mouse
- Mouse Anti-Tau Antibody (clone Tau5), mRNA (HPAB-S0178-YC-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, IF, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FuncS
- Human Anti-Tau Recombinant Antibody (HPAB-0773LY) (HPAB-0773LY)
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB, ELISA, IP, IHC, Neut
- Human Anti-Tau Recombinant Antibody; Fab Fragment (TAB-527CT-F(E)) (TAB-527CT-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB, ELISA, IHC
- Anti-Human Tau Recombinant Antibody Fab Fragment (ADx202) (TAB-528CT-F(E))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: WB, ELISA, IHC
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-529CT-F(E)) (TAB-529CT-F(E))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, IF, IHC
- Anti-Human Tau Recombinant Antibody Fab Fragment (pT231/pS235_1) (TAB-530CT-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Application: WB, ELISA, IP, IHC
- Anti-Human Tau Recombinant Antibody Fab Fragment (pT212/pS214_2) (TAB-531CT-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Application: WB, ELISA, IP, IHC
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-520CT-F(E)) (TAB-520CT-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-521CT-F(E)) (TAB-521CT-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-522CT-F(E)) (TAB-522CT-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-523CT-F(E)) (TAB-523CT-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: WB, ELISA, IHC
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: WB, ELISA, IHC
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-535CT-S(P)) (TAB-535CT-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, IHC
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-536CT-S(P)) (TAB-536CT-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, IHC
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-537CT-S(P)) (TAB-537CT-S(P))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IF
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-538CT-S(P)) (TAB-538CT-S(P))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IF
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-539CT-S(P)) (TAB-539CT-S(P))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IF
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-519CT-F(E)) (TAB-519CT-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-529CT-S(P)) (TAB-529CT-S(P))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, IF, IHC
- Anti-Human Tau Recombinant Antibody scFv Fragment (pT231/pS235_1) (TAB-530CT-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Application: WB, ELISA, IP, IHC
- Anti-Human Tau Recombinant Antibody scFv Fragment (pT212/pS214_2) (TAB-531CT-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Application: WB, ELISA, IP, IHC
- Anti-Human Tau Recombinant Antibody scFv Fragment (pS396/pS404_1) (TAB-532CT-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Application: WB, ELISA, IP, IHC
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-534CT-F(E)) (TAB-534CT-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, IHC
- Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-0773LY-F(E)) (HPAB-0773LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Anti-Human Tau Recombinant Antibody Fab Fragment (pS396/pS404_1) (TAB-532CT-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Application: WB, ELISA, IP, IHC
- Human Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-0773LY-S(P)) (HPAB-0773LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA
- Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2561LY-F(E)) (HPAB-2561LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB, IHC, ELISA
- Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2562LY-F(E)) (HPAB-2562LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB, IHC, ELISA
- Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2563LY-F(E)) (HPAB-2563LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB, IHC, ELISA
- Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2564LY-F(E)) (HPAB-2564LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB
- Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2565LY-F(E)) (HPAB-2565LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB
- Rabbit Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2566LY-F(E)) (HPAB-2566LY-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-538CT-F(E)) (TAB-538CT-F(E))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IF
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-539CT-F(E)) (TAB-539CT-F(E))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IF
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2567LY-F(E)) (HPAB-2567LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: IP, WB
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2568LY-F(E)) (HPAB-2568LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: IP, WB
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2569LY-F(E)) (HPAB-2569LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: IP, WB
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2570LY-F(E)) (HPAB-2570LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: IP, WB
- Human Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2561LY-S(P)) (HPAB-2561LY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, IHC, ELISA
- Human Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2562LY-S(P)) (HPAB-2562LY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, IHC, ELISA
- Human Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2563LY-S(P)) (HPAB-2563LY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scfv
- Application: WB, IHC, ELISA
- Human Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2564LY-S(P)) (HPAB-2564LY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scfv
- Application: WB
- Mouse Anti-Tau Recombinant Antibody (clone Tau5); Fab Fragment (HPAB-S0178-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-Tau Recombinant Antibody (clone Tau5); scFv Fragment (HPAB-S0178-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Recombinant Human Anti-Tau Antibody Fab Fragment (MHH-951-F(E))
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- Derivation: Human
- Type: Fab
- Application: ELISA, WB, FC, FuncS
- Recombinant Human Anti-Tau Antibody scFv Fragment (MHH-951-S(P))
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- Derivation: Human
- Type: scFv
- Application: ELISA, WB, FuncS
- Recombinant Anti-Tau Antibody Fab Fragment (MOB-951-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: IP, FuncS
- Recombinant Anti-Tau Antibody scFv Fragment (MOB-951-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: FC, Neut, Funcs
- Mouse Anti-Tau Recombinant Antibody (clone MHT2); scFv Fragment (FAMAB-0352WJ-S(P))
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, IHC
- Mouse Anti-Tau Recombinant Antibody (clone MHT2); Fab Fragment (FAMAB-0352WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB, IHC
- Human Anti-Tau Recombinant Antibody; Fab Fragment (MOB-0054SW-F(E)) (MOB-0054SW-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FuncS
- Human Anti-Tau Recombinant Antibody; scFv Fragment (MOB-0054SW-S(P)) (MOB-0054SW-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FuncS
- Human Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2565LY-S(P)) (HPAB-2565LY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scfv
- Application: WB
- Rabbit Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2566LY-S(P)) (HPAB-2566LY-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: WB
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2567LY-S(P)) (HPAB-2567LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: IP, WB
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2568LY-S(P)) (HPAB-2568LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: IP, WB
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2569LY-S(P)) (HPAB-2569LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: IP, WB
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-2570LY-S(P)) (HPAB-2570LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: IP, WB
- Anti-Human Tau Recombinant Antibody scFv Fragment (ADx202) (TAB-528CT-S(P))
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: WB, ELISA, IHC
- Mouse Anti-Tau Recombinant Antibody (TAB-538CT) (TAB-538CT)
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, IF
- Mouse Anti-Tau Recombinant Antibody (TAB-539CT) (TAB-539CT)
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IF, WB
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-519CT-S(P)) (TAB-519CT-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-520CT-S(P)) (TAB-520CT-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-521CT-S(P)) (TAB-521CT-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-534CT-S(P)) (TAB-534CT-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, IHC
- Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-523CT-S(P)) (TAB-523CT-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: WB, ELISA, IHC
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: WB, ELISA, IHC
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: WB, ELISA, IHC
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-536CT-F(E)) (TAB-536CT-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, IHC
- Mouse Anti-Tau Recombinant Antibody; Fab Fragment (TAB-537CT-F(E)) (TAB-537CT-F(E))
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IF
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Application: WB, ELISA, IHC
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For Research Use Only. Not For Clinical Use.
Background
Immunotherapies designed to treat neurodegenerative tauopathies that primarily engage extracellular tau may have limited efficacy as tau is primarily intracellular. We generated tau-targeting single-chain variable fragments (scFvs) and intrabodies (iBs) from the phosphorylated tau-specific antibodies CP13 and PHF1 and the pan-tau antibody Tau5. Recombinant adeno-associated virus (rAAV) was utilized to express these antibody fragments in homozygous JNPL3 P301L tau mice. Two iBs (CP13i, PHF1i) and one scFv (PHF1s) abrogated tau pathology and delayed time to severe hindlimb paralysis. In a second tauopathy model (rTg4510), CP13i and PHF1i reduced tau pathology, but cognate scFvs did not. These data demonstrate that (1) disease-modifying efficacy does not require antibody effector functions, (2) the intracellular targeting of tau with phosphorylated tau-specific iBs is more effective than extracellular targeting with the scFvs, and (3) robust effects on tau pathology before neurodegeneration only resulted in modest disease modification as assessed by delay of severe motor phenotype.