Human Anti-VEGFR2 Recombinant Antibody (TAB-0021CL)

CAT#: TAB-0021CL

This product is a recombinant human antibody that recognizes VEGFR2 (vascular endothelial growth factor receptor II). The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.

Specifications

  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Human IgG1
  • Antibody Isotype
  • IgG1
  • Specificity
  • Human VEGFR2 (vascular endothelial growth factor receptor II)
  • Species Reactivity
  • Does not bind to mouse VEGFR2
  • Applications
  • ELISA, Block
  • Related Disease
  • Vascular diseases

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • See the COA
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • KDR; kinase insert domain receptor; FLK1; CD309; VEGFR; VEGFR2; vascular endothelial growth factor receptor 2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor; kinase insert domain receptor (a type III receptor tyrosine kinase);
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Breast cancer biomarkers at key points during disease progression
No Cross-Reactivity With Mouse
We needed an antibody specific for human VEGFR2 that would not interfere with mouse receptors in our xenograft models. This recombinant human antibody fit the bill perfectly, showing zero cross-reactivity with mouse VEGFR2 while maintaining high affinity for the human protein.
Breast cancer biomarkers at key points during disease progression
Effective Blocking Antibody
We utilized this antibody for blocking assays to inhibit VEGFR2 signaling in vitro. It was highly effective and allowed us to study the receptor's pathway in detail. The purity was excellent, and it worked exactly as described for ELISA applications as well.

Q&As

  1. Does this antibody cross-react with mouse VEGFR2?

    A: No, this recombinant human antibody is specific to Human VEGFR2 and does not bind to mouse VEGFR2. It is designed to be specific for the human receptor, making it suitable for research where species specificity is required.

  2. What applications is this antibody used for?

    A: This antibody is suitable for Enzyme-linked Immunosorbent Assay (ELISA) and Blocking assays. It specifically recognizes Human VEGFR2 (vascular endothelial growth factor receptor II) and is purified by affinity chromatography.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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