Basiliximab (CAT#: TP-094CL)

A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha.

Isotype: Biotech


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Specifications

  • Type
  • Biotech
  • Trade name
  • Simulect
  • UNII
  • 9927MT646M

Target

  • Function
  • Chimeric (human/mouse) igG1 that blocks cellular immune response in graft rejection by binding the alpha chain of cD25 (iL2 receptor) and thereby inhibiting the iL2-mediated activation of lymphocytes

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "IGHG1"

Single-domain Antibody

CAT Product Name Application Type
NAB-1522-VHH Recombinant Anti-human IGHG1 VHH Single Domain Antibody Neut, ChiP, IP, FUNC Llama VHH

Recombinant Antibody

CAT Product Name Application Type
MOB-1117z Mouse Anti-IGHG1 Recombinant Antibody (clone 5C2) FC, IF, IHC, WB Mouse IgG1, κ
PABL-599 Human Anti-IGHG1 Recombinant Antibody (clone 2095-2) WB, ELISA, FuncS Chimeric (rabbit/human) IgG
PABL-600 Human Anti-IGHG1 Recombinant Antibody (clone C2095) WB, ELISA, FuncS Chimeric (rabbit/human) IgG
PABL-601 Human Anti-IGHG1 Recombinant Antibody (clone QAA-2095-2) WB, ELISA, FuncS Chimeric (rabbit/human) IgG
MOB-034LC Mouse Anti-IGHG1 Recombinant Antibody (clone YC121) ELISA, WB, IHC Mouse IgG

Fab Fragment Antibody

CAT Product Name Application Type
PFBL-594 Human Anti-IGHG1 Recombinant Antibody (clone 2095-2); Fab Fragment WB, ELISA, FuncS Chimeric (rabbit/human) Fab
PFBL-595 Human Anti-IGHG1 Recombinant Antibody (clone C2095); Fab Fragment WB, ELISA, FuncS Chimeric (rabbit/human) Fab
PFBL-596 Human Anti-IGHG1 Recombinant Antibody (clone QAA-2095-2); Fab Fragment WB, ELISA, FuncS Chimeric (rabbit/human) Fab

scFv Fragment Antibody

CAT Product Name Application Type
PSBL-594 Rabbit Anti-IGHG1 Recombinant Antibody (clone 2095-2); scFv Fragment WB, ELISA, FuncS Rabbit scFv
PSBL-595 Rabbit Anti-IGHG1 Recombinant Antibody (clone C2095); scFv Fragment WB, ELISA, FuncS Rabbit scFv
PSBL-596 Rabbit Anti-IGHG1 Recombinant Antibody (clone QAA-2095-2); scFv Fragment WB, ELISA, FuncS Rabbit scFv

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1394 Rabbit Anti-IGHG1 Recombinant Antibody (clone DS1394AB) ICC, IHC, FC, ELISA Rabbit IgG
MOR-1771 Rabbit Anti-IGHG1 Recombinant Antibody (clone DS1771AB), PE FC Rabbit IgG

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0577CQ Mouse Anti-IGHG1 Recombinant Antibody (clone B3-18) ELISA Mouse IgM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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