PE-A*02:01/Human IRF6 (GLYPGLIWL) MHC Tetramer (CAT#: MHC-LC1983)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human IRF6 of peptide GLYPGLIWL covering 21-29 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • IRF6
  • Antigen Species
  • Human
  • Peptide
  • GLYPGLIWL
  • Range
  • 21-29
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011]
  • Alternative Names
  • IRF6; Interferon regulatory factor 6; LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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