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    Mouse Anti-IRF6 Recombinant Antibody (clone ZN106) (CAT#: VS3-FY1584)

    This is a pathological recombinant antibody, which is a mouse IgG2b antibody. It exhibits high specificity and affinity for human IRF6. It can work in immunohistochemistry assay. The following concentration ranges are recommended starting points for this product: immunohistochemistry with a dilution of 1/50-1/100.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line HaCaT
    Figure 1 IF staining of human cell line HaCaT
    (Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm, cytosol & cell junctions.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/1576_F9_2_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/1685_F8_1_blue_red_green.jpg
    Normal Tissue
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Glial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Neuronal cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_B_9_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Glandular cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_9_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Hepatocytes
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_7_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in tubules
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_8_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Spermatogonia cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_6_6.jpg
    Figure 8 Skin
    Figure 8 Skin
    (Epidermal cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranousnucl ear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_B_5_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RT4)
    Figure 9 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RT4)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117595-IRF6

    Specifications

    • Host Species
    • Mouse
    • Type
    • Mouse IgG2b
    • Specificity
    • Human IRF6
    • Species Reactivity
    • Human
    • Clone
    • ZN106
    • Applications
    • Immunohistochemistry-Paraffin
    • Conjugate
    • Unconjugated
    • Related Disease
    • Popliteal Pterygium Syndrome and Orofacial Cleft 6

    Product Property

    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS (pH 7.3), 1% BSA, 50% glycerol
    • Preservative
    • 0.02% Sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • Immunohistochemistry: 1/50-1/100

    Target

    • Alternative Names
    • Interferon Regulatory Factor 6
    • Sequence Similarities
    • Belongs to the IRF family.
    • Cellular Localization
    • Cytoplasm, Nucleus
    • Post Translation Modifications
    • Ubl conjugation
    • Function
    • Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity).
      Plays a role in regulating mammary epithelial cell proliferation (By similarity).
      May regulate WDR65 transcription (By similarity).

    Recommended Products

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "IRF6"

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    CAT Product Name Application Type
    NAB-1969-sdAb Recombinant Anti-human IRF6 VHH Single Domain Antibody ELISA, Neut, ICC, FC Llama VHH
    FAMAB-0332-CN-VHH Camelid Anti-IRF6 Recombinant Single Domain Antibody (FAMAB-0332-CN-VHH) ELISA Camelid VHH
    FAMAB-0333-CN-VHH Camelid Anti-IRF6 Recombinant Single Domain Antibody (FAMAB-0333-CN-VHH) ELISA Camelid VHH
    FAMAB-0334-CN-VHH Camelid Anti-IRF6 Recombinant Single Domain Antibody (FAMAB-0334-CN-VHH) ELISA Camelid VHH

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