Recombinant Human Anti-Human IRF6 Antibody, clone U69
CAT#: DrMAB-356
Recombinant Human Antibody binds selectively to Human IRF6, expressed in E. coli.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm, cytosol & cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/1576_F9_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/1685_F8_1_blue_red_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Spermatogonia cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_6_6.jpg
Normal Tissue
Figure 8 Skin
Epidermal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranousnucl ear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_B_5_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117595-IRF6
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Type
- IgG
- Specificity
- reacts with human IRF6
- Species Reactivity
- Human
- Clone
- U69
- Applications
- IP; IF
Product Property
- Storage
- short term – store at 4°C (over 6 months), long term - PBS -20°C or -80°C
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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|---|---|---|---|
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| FAMAB-0333-CN-VHH | Camelid Anti-IRF6 Recombinant Single Domain Antibody (FAMAB-0333-CN-VHH) | ELISA | Camelid VHH |
| FAMAB-0334-CN-VHH | Camelid Anti-IRF6 Recombinant Single Domain Antibody (FAMAB-0334-CN-VHH) | ELISA | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1956 | PE-A2/Human IRF6 (GLYPGLIWL) MHC Tetramer | FCM | |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0872-CN | Recombinant Rabbit Anti-IRF6 Monoclonal Antibody (CBACN-324) | WB, IF, IHC | Rabbit IgG |
| VS3-CJ130 | Rabbit Anti-IRF6 Recombinant Antibody (VS3-CJ130) | WB, ICC, IF, IHC | Rabbit IgG |
| VS3-FY1584 | Mouse Anti-IRF6 Recombinant Antibody (clone ZN106) | IHC-P | Mouse IgG2b |
| VS-0625-FY1436 | Human Anti-IRF6 Recombinant Antibody (clone 2506W1331) | ELISA, Spiked IP, IF | Human IgG1 |
| VS-0625-FY1437 | Human Anti-IRF6 Recombinant Antibody (clone 2506W1332) | Spiked IP, IF | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| VS-0525-XY3594 | Anti-Mouse IRF6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3593 | Anti-Human IRF6 Immunohistochemistry Kit | IHC |
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