PE-A2/Human IRF6 (GLYPGLIWL) MHC Tetramer
CAT#: MHC-LC1956
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human IRF6 of peptide GLYPGLIWL covering 21-29 and A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.









Specifications
- Allele
- A2
- Class
- Class I
- MHC Species
- Human
- Antigen
- IRF6
- Antigen Species
- Human
- Peptide
- GLYPGLIWL
- Range
- 21-29
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011]
- Alternative Names
- IRF6; Interferon regulatory factor 6; LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1
- Gene ID
- 3664
- UniProt ID
- O14896
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Datasheet
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COA
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