PE-A*02:01/Human PSCA (AILALLPAL) MHC Tetramer

CAT#: MHC-LC021

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of PSCA-derived peptide of AILALLPAL sequence covering 105-133 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 IF staining of human cell line HeLa Figure 2 IHC staining of human kidney Figure 3 Stomach Figure 4 Colon Figure 5 Kidney Figure 6 RNA cell line category: Cell line enhanced (CAPAN-2, HeLa, OE19, RT4)

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • PSCA
  • Antigen Species
  • Human
  • Peptide
  • AILALLPAL
  • Range
  • 105-133
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • PSCA; prostate stem cell antigen; PRO232
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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