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    Mouse Anti-PSCA Recombinant Antibody (clone mAb 8D11) (CAT#: HPAB-0287CQ)

    This product is a recombinant mouse antibody that can bind to human PSCA with high affinity.

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    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    Other Requirements:
    We require custom production
    • Published Data
    • Tested Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    FC

    Figure 3 A graph comparing the amount of Surface Versus internalized anti-PSCA monoclonal antibody for each of the antibodies as measured within 1 hour, by the intensity of the Cy3 fluorescence.

    Figure 3 A graph comparing the amount of Surface Versus internalized anti-PSCA monoclonal antibody for each of the antibodies as measured within 1 hour, by the intensity of the Cy3 fluorescence.

    FuncS

    Figure 4 Shows the growth of PC-3.gDPSCA tumors in mice treated with 3 of the anti-PSCA antibodies (6F8, 8D11, and 5F2) as compared to the negative control, anti-ragweed antibody. The antibodies were administered by intraperito neal injection starting one day prior to inoculation with PSCA-transfected PC-3 cells, followed by biweekly injec tions following cell inoculation. “RX” under the arrows indicates the time point (day) of injection of the antibodies into the mice.

    Figure 4 Shows the growth of PC-3.gDPSCA tumors in mice treated with 3 of the anti-PSCA antibodies (6F8, 8D11, and 5F2) as compared to the negative control, anti-ragweed antibody. The antibodies were administered by intraperito neal injection starting one day prior to inoculation with PSCA-transfected PC-3 cells, followed by biweekly injec tions following cell inoculation. “RX” under the arrows indicates the time point (day) of injection of the antibodies into the mice.


    Specifications

    • Immunogen
    • Human PSCA expressed in E.coli
    • Host Species
    • Mouse
    • Type
    • Mouse IgG2b
    • Specificity
    • Human PSCA
    • Species Reactivity
    • Human
    • Clone
    • mAb 8D11
    • Applications
    • FC, IHC, Cyt, FuncS

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • This antibody has been tested for use in Flow Cytometry, Cytotoxicity and Functional Assay. Please see the Published Data for further information.

    Target

    • Alternative Names
    • PSCA; prostate stem cell antigen; PRO232

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone mAb 8D11"

    See other products for "PSCA"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Human Antibody Products Mouse Antibody Products Humanized Antibody Products MHC Tetramer Products for Cancer ScFv Antibody Products Fab Antibody Products ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-1981z Mouse Anti-PSCA Recombinant Antibody (clone 24F5) WB, FC, IF Mouse IgG1, κ
    HPAB-0286CQ Human Anti-PSCA Recombinant Antibody (clone mAb 5F2) FC, IHC, FuncS Human IgG1
    HPAB-1900-FY Human Anti-PSCA Recombinant Antibody (HPAB-1900-FY) FC, Inhib, WB, ELISA Human IgG1
    VS7-0425-WR699 Mouse Anti-PSCA Recombinant Antibody (clone 5H5A7) ICC, FC Mouse IgG2a
    VS7-0425-WR700 Mouse Anti-PSCA Recombinant Antibody (clone 3F4E4) FC Mouse IgG1

    Customer Reviews and Q&As

    Customer Review Q&As

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    Reliable in Research
    I found the Mouse Anti-PSCA Recombinant Antibody to be incredibly reliable for my flow cytometry experiments. Its specificity enabled clear differentiation between PSCA expressing cells and controls, which is critical for my studies. The precision and reproducibility it offers have saved both time and resources.

    A Must for Cancer Studies
    This antibody has become indispensable in our cancer research lab. Its high specificity for PSCA ensures we get accurate flow cytometry results every time. I would recommend it to any researcher focusing on prostate and bladder cancer.

    Excellent Binding Affinity
    The binding affinity of this antibody to PSCA is impressive. It strengthens our confidence in the reproducibility and accuracy of high-throughput assays, becoming an essential tool in our research arsenal.

    Highly Recommend for Bladder Cancer
    For researchers investigating bladder cancer pathways, this antibody is a game-changer. Its reliability in detecting PSCA made significant contributions to our findings and understanding of disease mechanisms.

    A Researcher's Best Friend
    Having used various antibodies in the past, this recombinant product stands out for its performance in targeting PSCA without cross-reactivity issues, proving to be an excellent choice for our laboratory.

    Cite This Product

    To accurately reference this product in your publication, please use the following citation information:

    (Creative Biolabs Cat# HPAB-0287CQ, RRID: AB_3111382)

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