Recombinant Mouse Anti-Human DES Antibody (clone E44)
CAT#: MOB-1093MZ
This antibody is a recombinant mouse monoclonal antibody which specifically reacts with human DES.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to intermediate filaments.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18803/1161_A10_3_selected.jpg
Normal Tissue
Figure 2 High expression in skeletal muscle
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18803/43421_B_1_6_val_selected.jpg
Normal Tissue
Figure 3 Low expression in skin 1
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18803/43421_B_7_1_val_selected.jpg
Normal Tissue
Figure 4 High expression in heart muscle.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34/1988_B_5_6_selected.jpg
Normal Tissue
Figure 5 Skeletal muscle
Myocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18803/43421_B_1_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HSkMC, LHCN-M2, NB-4, RH-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000175084-DES
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Specifications
- Immunogen
- Human leiomyoma
- Host Species
- Mouse
- Type
- Mouse antibody
- Antibody Isotype
- IgG1
- Specificity
- Human DES
- Species Reactivity
- Human
- Clone
- E44
- Applications
- ICC, IF, IHC-Fr IHC-P, WB
Target
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Excellent Desmin Staining
We used this antibody for Immunofluorescence on tissue sections. It provided brilliant staining of Desmin filaments. It is a great marker for our research into leiomyoma and other muscle-related conditions, giving clear and specific signals.
Works In IHC And WB
This is a versatile antibody. We have successfully used it in Immunohistochemistry on paraffin sections and in Western Blot. It specifically reacts with human DES, making it a fundamental tool for our lab's cytoskeleton research projects.
Q&As
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What tissue types can I use this antibody on?
A: This antibody is validated for Immunohistochemistry on frozen (IHC-Fr) and paraffin (IHC-P) sections. It specifically reacts with human DES (Desmin). It is also suitable for Immunocytochemistry (ICC), Immunofluorescence (IF), and Western Blot (WB).
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What is the immunogen used for this Desmin antibody?
A: The antibody was raised against Human leiomyoma, and it recognizes Human DES. Desmin is a muscle-specific intermediate filament protein. This recombinant mouse monoclonal antibody (clone E44) is an IgG1 isotype expressed in CHO cells.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| MOB-1487z | Mouse Anti-DES Recombinant Antibody (clone 25C5) | WB, ELISA, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
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| MOR-0971 | Hi-Affi™ Rabbit Anti-DES Recombinant Antibody (clone DS971AB) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0472-CN | Mouse Anti-DES Recombinant Antibody (clone 3-F7) | WB, IF, IHC, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0473-CN | Rabbit Anti-DES Recombinant Antibody (clone CBACN-194) | WB, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1813-CN | Rabbit Anti-DES Polyclonal Antibody (MRO-1813-CN) | WB, IF, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0087-FY | Rabbit Anti-DES Recombinant Antibody (clone AFY0058) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0001C | Mouse Anti-DES Recombinant Antibody (clone ABT-DES) | IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX325 | Mouse Anti-DES Recombinant Antibody (clone 290CT7.1.1) | WB | Mouse IgM, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY161 | Mouse Anti-NHP DES Recombinant Antibody (clone D33) | WB, IHC, IF | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC298 | CytoStream™ Rabbit Anti-DES Recombinant Antibody (VS13-YC298) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1976 | Anti-DES Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1977 | Anti-Mouse DES Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1978 | Anti-Rat DES Immunohistochemistry Kit | IHC |
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