+ Filter
Loading...
DES
Loading...Anti-DES Products
- Mouse Anti-DES Recombinant Antibody (clone 3-F7) (MRO-0472-CN)
-
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, IF, IHC, FC
Compare
- Rabbit Anti-DES Recombinant Antibody (clone CBACN-194) (MRO-0473-CN)
-
- Species Reactivity: Human, Mouse, Rat, Zebrafish
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
Compare
- Rabbit Anti-DES Polyclonal Antibody (MRO-1813-CN) (MRO-1813-CN)
-
- Species Reactivity: Human, Mouse, Zebrafish
- Type: Rabbit IgG
- Application: WB, IF, IHC
Compare
- Rabbit Anti-DES Recombinant Antibody (VS3-CJ719) (VS3-CJ719)
-
- Species Reactivity: Human, Mouse, Rat, Zebrafish
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, FC
Compare
- Mouse Anti-DES Recombinant Antibody (VS4-WK141) (VS4-WK141)
-
- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: ELISA, IHC
Compare
-
- Species Reactivity: Chicken, Human, Mouse, Rabbit, Rat, Pig
- Type: Mouse IgG1
- Application: IHC-Fr, IHC-P, WB
Compare
-
- Species Reactivity: Chicken, Dog, Hamster, Human, Mouse, Rabbit, Rat, Pig, Zebrafish
- Type: Mouse IgG2b
- Application: ICC, IHC-Fr
Compare
- Mouse Anti-DES Recombinant Antibody (VS3-CJ718) (VS3-CJ718)
-
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC
Compare
-
- Species Reactivity: Human, Hamster, Rat, Chicken
- Type: Mouse IgG1
- Application: ICC, IHC-Fr, IHC-P, WB
Compare
- Mouse Anti-DES Recombinant Antibody (clone 25C5) (MOB-1487z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, IHC
Compare
- Mouse Anti-NHP DES Recombinant Antibody (clone D33) (VS-1024-XY161)
-
- Species Reactivity: Bovine, Dog, Hamster, Human, Non-human primate, Rat
- Type: Mouse IgG1, kappa
- Application: WB, IHC, IF
Compare
- Rabbit Anti-DES Recombinant Antibody (clone AFY0058) (MOR-0087-FY)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: ICC, IHC-P, WB
Compare
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-p, IF, ELISA
Compare
- Anti-DES Immunohistochemistry Kit (VS-0525-XY1976)
-
- Species Reactivity: Human
- Target: DES
- Application: IHC
Compare
- Anti-Mouse DES Immunohistochemistry Kit (VS-0525-XY1977)
-
- Species Reactivity: Human, Mouse, Rat, Chicken, Hamster
- Target: DES
- Application: IHC
Compare
- Anti-Rat DES Immunohistochemistry Kit (VS-0525-XY1978)
-
- Species Reactivity: Human, Rat, Chicken, Hamster
- Target: DES
- Application: IHC
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Cardiomyocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HSkMC, LHCN-M2, NB-4, RH-30)
Interaction
Homomer (PubMed:21135508). Interacts with DST (By similarity). Interacts with MTM1 (PubMed:21135508). Interacts with EPPK1; interaction is dependent of higher-order structure of intermediate filament (PubMed:16923132). Interacts with CRYAB (PubMed:28470624). Interacts with NEB (via nebulin repeats 160-164) (PubMed:23615443). Interacts (via rod region) with NEBL (via nebulin repeats 1-5) (PubMed:27733623). Interacts with ASB2 isoform 1; the interaction targets DES for proteasomal degradation (By similarity).
Molecular function
Muscle protein
More Types Infomation