Recombinant Human Anti-EGFRvIII Antibody
CAT#: MHH-310
Recombinant Human Antibody recognizes and binds to EGFRvIII, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-EGFRvIII mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-EGFRvIII mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specifications
- Immunogen
- EGF receptor variant III
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native EGF receptor variant III
- Applications
- Antibody assay: Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functional Study
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- EGF receptor variant III; EGFRvIII
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Customer Review
There are currently no Customer reviews or questions for MHH-310. Click the button above to contact us or submit your feedback about this product.
Very Reliable Tool
I have been using the Recombinant Human Anti-EGFRvIII Antibody for my research for several months. It has been very reliable in ELISA tests. The product offers strong and consistent binding to EGFRvIII, which is essential for my studies on cell signaling. I love that it comes with complete documentation and support. The flexible size options and quality control data make it a well-rounded choice. I highly recommend this antibody for any non-clinical research projects as it has helped me get clear, reproducible results every time.
Works as Expected
This product works exactly as I expected for my research studies. I use it routinely for ELISA and Immunofluorescence to track EGFRvIII protein presence in my samples. The quality control measures and high purity guarantee a consistent experience. It is easy to work with, and I have not faced any challenges regarding storage or handling. The option to choose various sizes makes it adaptable to both small and large projects. I am happy with its reliable performance and clear documentation that supports all my experimental needs.
Consistent Results
I use the Recombinant Human Anti-EGFRvIII Antibody in daily research work and have been impressed by its consistency. It provides stable results in various assays such as immunofluorescence and Western blot. The detailed certificate of analysis and clear quality metrics give me confidence in its use. I find it easy to handle and store as instructed, which adds to its reliability.
Q&As
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What research applications can I use the Anti-EGFRvIII Antibody for?
A: You can use this antibody in many lab experiments such as ELISA, functional studies, and immunofluorescence. It is designed to bind to the EGFRvIII target, which is a mutated form of the epidermal growth factor receptor. This makes it a great tool for studying cell signaling and protein interactions in research. The clear and strong signal helps you to get reliable data in multiple experimental setups.
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What is special about the EGFRvIII target?
A: EGFRvIII is a mutant variant of the EGFR receptor that researchers study under controlled lab settings. This antibody is made to bind specifically with the EGFRvIII variant. It helps in QAealing complex protein interactions and signaling pathways in experiments.
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What are the recommended storage conditions for this antibody?
A: You need to store the antibody at -20°C to ensure its stability and activity over time. The instructions advise that once reconstituted, it should be aliquoted if not used within two weeks. Following these guidelines save your time. This clear storage instruction helps you plan your experiments better and keeps the antibody working well throughout research projects.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "EGFRvIII"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-310 | Recombinant Anti-EGFRvIII Antibody | ELISA, WB, Dot, FuncS | IgG |
| HPAB-0111LY | Mouse Anti-EGFRvIII Recombinant Antibody (HPAB-0111LY) | FC, Cyt | Mouse IgG |
| HPAB-0483LY | Human Anti-EGFRvIII Recombinant Antibody (clone CBL009LY) | ELISA | Human IgG |
| HPAB-0138-YJ | Human Anti-EGFRvIII Recombinant Antibody (HPAB-0138-YJ) | ELISA, Inhib, FuncS | Human IgG1, κ |
| HPAB-0662-WJ | Human Anti-EGFRvIII Recombinant Antibody (HPAB-0662-WJ) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-310-F(E) | Recombinant Anti-EGFRvIII Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| HPAB-M0065-YC-F(E) | Human Anti-EGFRvIII Recombinant Antibody; Fab Fragment (HPAB-M0065-YC-F(E)) | FC, Block, FuncS | Human Fab |
| HPAB-M0066-YC-F(E) | Mouse Anti-EGFRvIII Recombinant Antibody; Fab Fragment (HPAB-M0066-YC-F(E)) | FC | Mouse Fab |
| HPAB-M0067-YC-F(E) | Human Anti-EGFRvIII Recombinant Antibody; Fab Fragment (HPAB-M0067-YC-F(E)) | FC | Human Fab |
| HPAB-0662-WJ-F(E) | Human Anti-EGFRvIII Recombinant Antibody; Fab Fragment (HPAB-0662-WJ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-310-S(P) | Recombinant Anti-EGFRvIII Antibody scFv Fragment | Neut, WB, FuncS | scFv |
| MHH-310-S(P) | Recombinant Human Anti-EGFRvIII Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| HPAB-0483LY-S(P) | Human Anti-EGFRvIII Recombinant Antibody (clone CBL009LY); scFv Fragment | ELISA | Human scFv |
| HPAB-648-FY-S(P) | Human Anti-EGFRvIII Recombinant Antibody; scFv Fragment (HPAB-648-FY-S(P)) | FC, ELISA | Human scFv |
| HPAB-0138-YJ-S(P) | Human Anti-EGFRvIII Recombinant Antibody (HPAB-0138-YJ-S(P)); scFv Fragment | ELISA, Inhib, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC111 | SmartAb™ Recombinant Anti-EGFRvIII pH-dependent Antibody (VS-0825-YC111) | ELISA, Inhib | Human IgG1 kappa |
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